摘要
目的:对肠外营养(PN)的不良反应和并发症的发生率、临床表现及发生机制进行调研和文献复习。方法:从全军药品不良反应监察中心数据库1995~1998年调出2947条药物不良反应,检索国内PN不良反应及并发症的有关文献。结果:全军不良反应监察中心数据库中调出PN不良反应59例,占2%。PN支持中主要并发症有肠源性感染、淤胆等。结论:应用PN支持时,应全面综合考虑疗效-副作用-价格三方面因素,正确合理应用营养支持。
Objective: To review PN-caused adverse reactions, complications, clinical manifestation and patho-genesis. Methods: 2947 entries (1995-1998) from the data bank of all-army ADR monitoring center were analysed together with the references retrieved. Results: 59 cases of PN-ADR accounted for 2% . Major complications of PN were enterogenous infection and cholestasis. Conclusion: PN support therapy needs balance of its efficacy, side effect and cost so as to use it rationally.
出处
《药物不良反应杂志》
2000年第2期98-102,共5页
Adverse Drug Reactions Journal