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应用随机双盲法观察苦碟子注射液治疗冠心病心绞痛的疗效 被引量:7

THE EFFICACY OF“KU DIE Zl”INFUSION IN THE MANAGEMENT OF ANGINA PECTORIS WITH CORONARY HEART DISEASE
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摘要 选择冠心病心绞痛312例随机分成3组治疗,以验证苦碟子的疗效。其中甲,乙二组为双盲对照。甲组110例用苦碟子注射液治疗。乙组104例用复方丹参注射液治疗。丙组98例用低分子右旋糖酐注射液治疗。其症状有效率甲、乙、丙三组分别为90.9%、86.5%和89.8%。三组间无显著差异。心电图有效率甲、乙、丙三组分别为51.8%、38.5%和61.2%。甲与乙,丙二组相比均无显著差异(P>0.05)。在苦碟子组治疗中仅1例大便稀溏。作者认为,苦碟子可以作为治疗冠心病心绞痛的有效药物。值得推广应用。 To determine the efficacy of 'Ku Die Zi' infusion 312 patients were selected and randomized into three groups.Groups A and B compared in a double blind way.'Ku Die Zi' infusion was used in 110 patients of group A,and injection salviae miltiorrhizae composita in 104 patients of group B,and low-molecule Dextran infusion in 98 patients of group C.The rates of improvement of symptoms were 90.9%,86.6%,and 89.8%,respectively,in the three groups.The rates of improvement of ECG were 51.8%,38.5% and 61.2%,respectively.There was no significant difference between groups A and B and A and C (both P>0.05).One of the cases had loose stools during the treatment with 'Ku Die Zi' infusion.It was believed that 'Ku Die Zi' infusion was a valuable drug for further clinical trial.
出处 《解放军医学杂志》 CAS CSCD 北大核心 1989年第1期30-32,共3页 Medical Journal of Chinese People's Liberation Army
关键词 冠心病 苦碟子 疗效观察 Ixeris sonchifolia Hance Low-molecule dextran Angina pectoris of coronary heart disease
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