摘要
目的 探讨联合应用培哚普利 (商品名 :雅施达 )和吲哒帕胺 (商品名 :纳催离 )逆转高血压病左心室肥厚的疗效。方法 将 82例高血压病左心室肥厚患者应用培哚普利 4mg/d和吲哒帕胺 2 5mg/d ,治疗时间 1年 ,并通过超声心动图分别测定治疗前后左心室舒张末内径、舒张期室间隔厚度、左室后壁厚度。结果 治疗前后比较 ,左心室舒张末内径、舒张期室间隔厚度、左室后壁厚度有明显下降 (P <0 0 1)。结论 两药合用有明显降压效果 ,对原发性高血压疗效显著 。
Objective To study the effect of combined treatment by perindopril and indapamide on regressing left ventricular hypertrophy in essential hypertension. Methods 82 patients with hypertension accompained by left ventricular hypertrophy were given perindopril 4 mg/d and Indapamide 2 5 mg/d for one year, and were surveied LVDd,IVST,LVPWT by Echocardiography before and after treatment. Results LVDd,IVST, LVPWT became significantly thiner ( P <0 01) after treatment. Conclusions Theperin dopril combined with Indapamide treatment has good effacts for essential hypertension. It could decrease blood pressure significantly and regress left ventricular hypertrophy.
出处
《岭南心血管病杂志》
2003年第5期324-325,共2页
South China Journal of Cardiovascular Diseases
