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冠心病患者血浆内皮素和降钙素基因相关肽检测的临床意义

Measurement of plasma endothelin(ET) and calcitonin gene-related peptide(CGRP) in patients with coronary heart disease and their clinical significance
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摘要 目的 探讨内皮素 (ET)和降钙素基因相关肽 (CGRP)在冠心病患者中的作用。方法 应用放射免疫法对 36例冠心病进行了血浆ET、CGRP水平测定 ,并与 35名正常健康人作对照。结果 冠心病患者血浆ET水平高于正常人组 (P <0 .0 1)、CGRP水平低于正常人组 (P <0 .0 1)。 Objective To explore the effect of detection of the levels of plasma ET and CGRP in patients with coronary heart disease.Methods Thirty six patients with coronary heart disease were tested by radioimmunoassay(RIA) for the levels of plasma ET and CGRP and thirty five normal controls were also tested.Results The level of plasma ET in coronary heart disease groups was obviously higher than that in normal control( P < 0.01 ).While CGRP levels were lower than that in normal controls( P < 0.01 ).Conclusion Plasma ET and CGRP levels are closely related the occurrence and development in patients with coronary heart disease.
作者 纪树岚
出处 《淮海医药》 2003年第6期449-450,共2页 Journal of Huaihai Medicine
关键词 冠心病 内皮素 降钙素基因相关肽 放射免疫法 Coronary disease Endothelin Calcitonin gene related peptide
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