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即刻早期和晚期基因的转录产物在巨细胞病毒感染中的诊断作用 被引量:1

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摘要 近年来对于巨细胞病毒 (CMV)的即刻早期 (IE)基因和晚期 (L)基因的结构和功能有了较为深入的研究。应用核酸杂交技术和聚合酶链反应等先进技术检测IE -mRNA和L -mRNA能在早期特异性地诊断CMV活动性感染 ,对于临床治疗和预后监测有重要的指导意义。
出处 《中国优生与遗传杂志》 2003年第5期137-138,14,共3页 Chinese Journal of Birth Health & Heredity
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  • 1Peckham CS. Cytomegaolvirus infection: congenital and neonatal disease[ P ]. Stand J Infect Suppl, 1991,78: 82 - 87.
  • 2Boppana S, Pass RF, Britt WS, et al. Symptomatic congenital cytomegalovirus infection: neonatal and mortality[J]. Pediatr Infect Dis J, 1992,11:93 - 99.
  • 3Velzing J, Rothbarth, Kroes ACM, et al. Detection of cytomegalovirvs mRNA and DNA encoding the immediate early gene in peripheral blood leukocyte from immunocompromised patients[J ]. J Med Virol, 1994, 42:164 - 169.
  • 4Snaar SP, Verdijk P, Tanke HT, et al. Kinetics of HCMV immediate early mRNA expression in stably transfected fibroblasts [ J ]. J Cell Sci, 2002,115(pt2) : 321 - 328.
  • 5McElroy AK, Dwarakanath RS, Spector DH, et al. Dysregulation of cyclin E gene expression in human cytomegaolvirus- infected cells requires viral early gene expression and is associated with changes in the Rb - relatedprotein P130[J ]. JVirol, 2000, 74(9) :4192.
  • 6Chiou SH, Liu JH, HSu WM, et al. Up - regulation of Fad ligand expression by human eytomegalovurus immediate - early gene produets2: a novel mechanism in eytomegalovirus - induced apoptosis in human retina[J]. J Immunol, 2001, 167(7) :4098 - 4103.
  • 7Hummel M, Zhang Z, Yan S, et al. Allogeneic transplantation induces expression of cytomegalovirus immediate- early genes in vivo:a model for reactivation from latency [J ]. J Virol, 2001, 75 ( 10 ) :4814 - 4822.
  • 8Liu Y, Biegalke BJ. The human cytomegalovirus UL35 gene encodes two proteins with different functions[J]. J Virol, 2002, 76(5) :2460.
  • 9Van MP, Dirks RW, Van RP, et al. Fluorescence in situ hybridization using horseradish peroxidase - labeled oligodeoxynucleotides and tyramide signal amplification for sensitive DNA and mRNA detection[J]. Histochem Cell Biol, 1998,110(4) :431 - 437.
  • 10Gozhan J, Salord JM, Chouaid C, et al. Human cytomegalovirus(HCMV) late - mRNA detection in peripheral holld d AIDS patients: diagnostic value for HCMV disease compared with those of viral culture and HCMV DNA detection [ J ]. J Clin Microbiol,1993.31(7) : 1943 - 1945.

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