摘要
本文报道肾穿刺活检50例成人肾病综合征,原发性:继发性为2.57:1。慢性肾炎最多,占总数58％,急性肾炎14％,LE肾炎占20％,居继发性首位,其它较少见。肾病理以局灶硬化最多(24％),膜性肾炎次之(18％)。各临床类型的肾脏病理有其一定特征。在原发性与继发性之间,贫血、γ球蛋白下降、C_3、CH_(50)及莫氏试验等的异常有显著差异。LE肾炎、急性肾炎伴高血压、肾功能不全较多,前者血尿少,贫血重;后者血尿显著,贫血少。激素疗效以弥漫增殖性最差,膜性次之,微小病变型最佳。
The results of renal biopsy of 50 adults with nephrotic syndrome are reported. The ratio between primary and secondary types was 2.5:1. Chronic nephritis was the most frequent cause (58%), and then LE nephritis (20%) and acute nephritis (14%), whereas LE nephritis was the most important cause in secondary type. Pathologically, focal sclerosis was the prominent renal lesion (24%) and membranous nephritis was less frequent (18%). Different chronic types had their characteristic renal pathology. Significant different degrees of anemia, γ-globulin, C3 and CH50 were observed between primary and secondary cases. LE nephritis and acute nephritis were more frequently complica ted with hypertension and renal insufficiency; nevertheless, mild hematuria and severe anemia occurred in LE nephritis, and marked hematuria and mild anemia developed in acute nephritis. The response to steroid therapy was found poor in diffuse proliferative type, better in membraneous type and best in those cases with minimal lesion.
出处
《上海医学》
CAS
CSCD
北大核心
1992年第8期444-447,共4页
Shanghai Medical Journal
关键词
肾病综合征
临床和病理
Nephrotic syndrome
Pathologic findings
steroid therapy
