摘要
本文分析初诊151例非胰岛素依赖型糖尿病(NIDDM)各年龄组频率分布、体重指数(BMI)、腰臀比率(WHR)及其它临床特征和糖、脂、胰岛素水平,并与>10年病程患者作一比较。1.初诊NIDDM患者发病年龄高峰为50～60岁,且伴有轻度超重与肥胖。2.60～岁和70～岁组高血压、冠心病、脑血管意外、白内障及眼底病变为多见。3.40～岁组血糖水平高于各组,而脂质及各脂蛋白亚组分在各年龄组中均无差异,胰岛素水平在60岁以上组为高。4 BMI、WHR、胰岛素值间均有较好相关(P均<0.05或0.01)。5.伴有合并症组BMI及胰岛素水平非常显著高于不伴合并症组(P<0.001)。6.与>10年病程比较,白内障、眼底病变有显著差异(P<0.01)。结果提示初诊NIDDM高发50～岁和60～岁组亦已有相当部分合并症,故早期详细了解病史与消除各种危险因素颇为重要。
The body mass index (BMI), waist-hip circumference ratio (WHR) and other clinical characteristics, and blood sugar, lipoid and insulin levels in different age groups were assayed in 151 patients initially diagnosed non-insulin dependant diabetes mellitus (NIDDM). Those of NIDDM patients with clinical course of more than 10 years were also observed for comparison. Results of the study showed: 1. The highest incidence of initially diagnosed NIDDM was found at the age of 50～60 years, with mild degree of overweight and obesity. 2. Hypertension, coronary heart disease, apoplexy, cataract and retinopathy were more common in patient>60 years. 3. Higher levels of blood sugar and insulin swere observed in age group of 40～ and more than 60 years respectively. However the blood levels of lipoid and lipoprotein showed no difference among different age groups. 4. BMI and WHR were well associated with insulin values (P<0.05, 0.01). 5. BMI and insulin levels were significantly higher in patients with complications than in patients without(P<0.001). 6. Development of cataract and retinopathy in those patients with clinical course more than 10 years also showed significant difference as compared with that of early NIDDM. Thus full investigation on early NIDDM and proper management of high risk factors are of the utmost importance.
出处
《上海医学》
CAS
CSCD
北大核心
1992年第3期154-158,共5页
Shanghai Medical Journal
关键词
年龄
临床特征
并发症
早期
糖尿病
Clinical characteristics
Blood biochemistry
Complications
Early diabetes mellitus
