摘要
目的 观察 9例心脏移植供、受者组织配型 ,分析其与心脏移植早期存活的关系。方法 应用国际标准方法 ,对 9例心脏移植供、受者进行血型、HLA抗原、淋巴细胞毒及群体反应性抗体等检测 ,并用氨基酸三联体及交叉反应组方法对供、受者匹配程度进行评价。结果 9例心脏移植 ,存活 6例 ,死亡 3例。其中综合评价配合最好的 2例及最差的 2例中各有 1例死亡。术后活检证实 ,存活及死亡病例均未发生排斥反应。结论 在有效的免疫抑制剂治疗下 ,HLA配型结果不影响移植物的早期存活。
Objective To evaluate the matching degree of donor's and receptor's tissue typing and analyze the relationship between the degree and the early survival of cardiac transplantation with donor's and receptor's tissue typing of 9 cases of cardiac transplantation. Methods In accordance with the international standard, donor's and receptor's blood type, HLA antibody, lymphocytotoxicity and panel reactive antibody were determined in 9 cases of cardiac transplantation, and the donor's and receptor's matching degree evaluated by methods of amino acid triplets and cross-reactive group. Results Of 9 cases, 6 survived while 3 died. Of the 3 dead cases, 2 came respectively from the two best comprehensively evaluated matching cases and two worst, and postoperative biopsy showed that there was no rejection in either survival cases or the dead cases. Conclusion With the effective immunosuppressant, the HLA typing doesn't affect the early survival.
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2003年第6期364-366,共3页
Chinese Journal of Organ Transplantation
