摘要
目的 探讨性激素在膀胱癌发病中的意义。方法 :采用放射免疫法检测 31例男性膀胱癌患者及 2 7例同年龄正常人对照组血清中的雌二醇 (EstradiolE2 )、孕酮 (ProgesteroneP)及睾酮 (TestosteroneT)水平。结果 :男性膀胱癌患者血清E2 、P、T分别为 44.98± 2 0 .96pg ml( x±s) ,0 .37± 0 .18ng ml( x±s) ,6 .2 5± 2 .37ng ml( x±s) ,而正常对照组E2 、P、T分别为 5 6 .0 1± 13.5 0pg ml( x±s) ,1.14± 0 .37ng ml( x±s) ,5 .15± 1.37ng ml( x±s) ,两者比较膀胱癌组T明显高于对照组 (P <0 .0 5 ) ;而E2 、P明显低于对照组 (P <0 .0 5 )。结论
Purpose: To study the importance of sex hormone for the incidence of bladder cancer. Methods: The serum estradiol (E 2), Progesterone (P) and testosterone(T) were measured in 31 case of male patients with bladder cancer and 27 normal men with radioimmunoassay.Results: The results showed:the serum E 2,P,T in male patients with bladder cancer were 44.98±20.96pg/ml(±s),0.37±0.18ng/ml(±s) and 6.25±2.37ng/ml(±s) respectively, Whereas,they were 56.01±13.50 pg/ml(±s),1.14±0.37ng/ml(±s) and 5.15±1.37ng/ml(±s) respectively in the age matched controls. T in patients was significantly higher than that in the age matched controls(P<0.05); but E 2 and P in patients were significantly lower than those in the age matched controls (P<0.05) . Conclusions: The results suggested that the incidence of bladder cancer may be implicated in the sex hormone disorders.
出处
《海南医学》
CAS
2001年第8期25-26,共2页
Hainan Medical Journal
