摘要
目的 :探讨流行性乙型脑炎 (乙脑 )患儿血清中神经元特异性烯醇酶 (NSE)含量的变化及临床意义。方法 :采用酶联免疫法测定 49例乙脑患儿和 15例对照组血清中NSE含量。结果 :49例乙脑患儿血清中NSE含量比15例对照组明显升高 ,差异有非常显著性意义 (t=3.5 6 ,P <0 .0 1)乙脑患儿血清中NSE含量 ,随着临床分型加重而升高 ,差异有非常显著性意义 (P <0 .0 1)。有后遗症组血清NSE含量比无后遗症组明显升高 ,差异有非常显著性意义 (t=3.71,P <0 .0 1)。结论
Objective To probe the change in Neuron-specific enolase(NSE) content of serum in children with epidemic encepha B, and its clinical significance. Methods ELISA was adopted to determine the NSE contents in the serums from 49 child cases of encephalitis B, and 15 healthy children(control group). Resulits The content of NSE in encephalitis B cases was higher than that of the control( t =3.56, P <0.01). The serum NSE level was also much higher in patients with complications than in those no complications( t =3.71, P <0.01). Conclusion Serum NSE content variations can be regarded as an important indication for brain damage and clinical prognosis and degree of brain damage.
出处
《郧阳医学院学报》
2001年第2期76-77,共2页
Journal of Yunyang Medical College
关键词
流行性乙型脑炎
小儿
血清
神经元特异性烯醇酶
含量测定
encephalitis, Japanese
phosphopyruvate hydratase
enzyme-linked immunosorbent assay
child
prognosis
