摘要
目的:了解干扰素的不良反应。方法:检索1993～2002年间国内医药学期刊有关文献,对干扰素引起的不良反应进行调查分析。结果:99例患者因使用干扰素发生不良反应153例次,用药初期多为流感样症状,反复多次用药后不良反应可累及多个器官/系统。结论:干扰素引起的不良反应大多轻微而可逆,但也有部分为严重的,甚至是致死的反应。提示临床应加强用药监测,以预防和减少不良反应的发生。
Objective:To review adverse reactions related to interferon.Method:Literature survey was based on national medical journals of1993-2002for analysis.Re sults:153adverse reactions of99cases taking interferon were reported.In the initial stage of therapy the commonest reactions were flu-like symptoms.After administration repeatedly,many organs/systems were involved.Con clusion:The adverse reactions of interferon are usually mild and re versible,rarely severe and fatal.Care should be taken in order to prevent and reduce the occurrence of unwanted reac tions.
出处
《药物不良反应杂志》
2003年第5期308-311,共4页
Adverse Drug Reactions Journal
