血小板源性生长因子神经保护作用的研究进展
被引量:2
摘要
血小板源性生长因子 (PDGF)是由多种细胞合成和分泌的多肽。PDGF及其受体在神经系统广泛表达 ,参与神经系统发育、成熟 ,对神经系统起营养保护作用 ,在多种神经系统疾病中起积极作用。
出处
《国外医学(生理病理科学与临床分册)》
2003年第5期516-518,共3页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
基金
国家自然科学基金 (3990 0 172 )
参考文献16
-
1Oya T,Zhao YL,Takagawa K,et al. Platelet-derived growth factor-b expression induced after rat peripheral nerve injuries [ J ]. Glia, 2002, 38:303-312.
-
2Hinks GL, Franklin RJ. Distinctive patterns of PDGF-A, FGF-2, IGF-1 and TGF-beta gene expression during remyelination of experimentally-induced spinal cord demyelination[ J]. Mol Cell Neursci, 1999, 14 : 153-168.
-
3Fruttiger M, Calver AR, Richardson WD, et al. Platelet-derived growth factor is constitutively secreted from neuronal cell bodies but not from axons[J]. Curr Biol, 2000, 10: 1283-1286.
-
4Ohno M, Sasahara M, Narumiga S, et al. Expression of platelet-derived growth factor B-chain and beta-receptor in hypoxic/ischemic encephalopathy of neonatal rats[ J ]. Neuroscience, 1999, 90:643-645.
-
5Mekada A, Sasahara M, Yamada E, et al. Platelet-derived growth factor B-chain expression in the rat retina and optic nerve: distribution and changes after transection of the optic nerve [ J ]. Version Res, 1998, 38:3031-3039.
-
6Erlandsson A, Enarsson M, Forsberg-Nilsson K, et al. Immature neurons rom CNS stem cells proliferate in response to platelet-derived growth factor[J]. J Neurosci, 2001 , 21:3483-3491.
-
7Caldwell MA, He X, Wilkie N, et al. Growth factors regulate the survival and fate of ceils derived from human neurospheres[ J ]. Nat Biotechnol, 2001, 19:475-479.
-
8Van Heyningen P, Calver AR, Richardson WD, et al. Control of progenitor cell number by mitogen supply and demand[ J ]. Curr Biol, 2001, 11:232-241.
-
9Sung JY, Lee SY, Min DS, et al. Differential activation of phospholipases by mitogenic EGF and neurogenic PDGF in immortalized hippocampal stem cell lines [ J ]. J Neurochem, 2001, 78 : 1044-53.
-
10Sims KD, Straff DJ, Robinson MB, et al. Platelet-derived growth factor rapidly increases activity and cell surface expression of the EAAC1 subtype of glutamate transporter through activation of phosphatidylinositol 3-kinase[ J]. J Biol Chem. 2000, 275:5225-5237.
同被引文献13
-
1Ulrich V M. Gene therapy methods in bone and joint disorders. Evaluation of the adeno-associated virus vector in experimental models of articular cartilage disorders, periprosthetic osteolysis and bone healing [J]. Acta Orthop Suppl, 2007, 78(325) : 1- 64.
-
2Sasahara M, Fries J W, Raines E W, et al. PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model [J]. Cell, 1991, 64(1): 217-227.
-
3Lonergan T, Teschemacher A G, Hwang D Y, et al. Targeting brain stem centers of cardiovascular control using adenoviral vectors: impact of promoters on transgene expression [ J ]. Physiol Genom, 2005, 20(2) : 165-172.
-
4Games D, Adams D, Messandrini R, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta- amyloid precursor protein [J]. Nature, 1995, 373 (6514): 523-527.
-
5Fruttiger M, Calver A R, Richardson W D. Platelet-derived growth factor is constitutively secreted from neuronal cell bodies but not from axons[J]. Curr Biol, 2000, 10(20):1283-1286.
-
6McKinnon R D, Waldron S, Kiel M E. PDGF alpha-receptor signal strength controls an RTK rheostat that integrates phosphoinositol 3'-kinase and phospholipase Cgamma pathways during oligodendrocyte maturation [ J]. J Neurosci, 2005, 25 (14) :3499-3508.
-
7咸海青,刘淑红,顾晓松,严志强,范明.rhCNTF对鸡胚感觉与运动神经元神经营养作用的比较[J].中国应用生理学杂志,1997,13(3):268-270. 被引量:6
-
8张键,陈峥嵘,陈中伟,张光健.睫状神经营养因子促进大鼠周围神经再生的实验研究[J].中华创伤杂志,1999,15(3):208-211. 被引量:7
-
9王廷华,吴良芳,廖德阳,周雪.成年猫L_6DRG神经元按大小分类的形态学证据[J].昆明医学院学报,2000,21(1):47-50. 被引量:21
-
10顾晓松,丁斐,刘炎,沈爱国,姚登兵.CNTF基因在大鼠脊髓中的表达及生后发育的变化[J].解剖学报,2001,32(4):305-308. 被引量:2
引证文献2
-
1张连双,章为,王廷华,徐新运,赵秀军,李永红,周雪.部分背根切断对备用背根节神经元CNTF、PDGF表达的影响[J].四川大学学报(医学版),2005,36(2):176-179. 被引量:2
-
2任凯,丁岩,崔云燕,杨玲玲,张静,崔行.神经特异性启动子PDGF-EGFP载体的构建及组织表达特异性鉴定[J].山东大学学报(医学版),2009,47(5):50-53. 被引量:2
二级引证文献4
-
1张连双,王希锋,李雅娜,张洪芹,赵伟,时彦,王东,刘桂香.CNTF、PDGF在成年猫背根节的分布[J].滨州医学院学报,2007,30(6):425-426.
-
2张连双,张洪芹,赵伟,章为,王廷华.针刺对备用背根节神经元CNTF和PDGF表达的影响[J].解剖学研究,2008,30(2):122-126. 被引量:1
-
3彭坚,李惠,涂知明.神经组织特异性启动子的研究方法和进展[J].中国优生与遗传杂志,2010,18(9):8-11. 被引量:2
-
4荣曼,张锐虎,刘田福.PDGF-GAL真核表达载体的构建及细胞表达[J].生物技术通报,2013,29(2):124-129.
-
1唐鹏,郭乔楠,姜军.PDGF家族新成员——PDGF-C[J].现代生物医学进展,2007,7(2):301-302. 被引量:3
-
2龚小卫,魏洁,李煜生,程蔚蔚,邓鹏,姜勇.p38 MAPK对PDGF诱导的细胞迁移的调控作用[J].解放军医学杂志,2007,32(3):205-207. 被引量:2
-
3张宗城,张积仁.鞘糖脂与信号转导[J].国外医学(生理病理科学与临床分册),2000,20(6):471-473.
-
4徐广明.脑膜瘤与血小板源生长因子[J].国外医学(神经病学.神经外科学分册),1998,25(6):307-309.
-
5周茂华,何煜,李卫华.衰老细胞的PDGF基因表达[J].武警医学院学报,2002,11(2):132-133.
-
6何扬涛,王丽雁,蔡文琴.大鼠脑中PDGFαR免疫反应阳性细胞与NG2免疫反应阳性细胞的比较[J].中国组织化学与细胞化学杂志,2009,18(4):478-479.
-
7孙月庭,刘斌剑.血小板源性生长因子的纯化及其生物活性的研究[J].武汉医学杂志,1996,20(3):186-187.
-
8NIE Jing HOU Fan-fan.Role of reactive oxygen species in the renal fibrosis[J].Chinese Medical Journal,2012(14):2598-2601. 被引量:7
-
9张舒,周杨,关思宇,梁霄玉,欧阳红生.血小板源性生长因子(PDGF-BB)促进山羊骨髓间充质干细胞向平滑肌细胞分化[J].中国兽医学报,2008,28(8):939-942. 被引量:3
-
10李培旺,冯争名,蒋丽娟,孙友平.毕赤酵母高效表达血小板源生长因子研究[J].生命科学研究,2005,9(4):346-350. 被引量:1