摘要
目的 :探讨新生儿感染性疾病中血清降钙素原 (PCT)和C反应蛋白 (CRP)的变化及其临床意义。方法 :检测 75例感染性疾病新生儿和 3 0例非感染性疾病新生儿血清中PCT、CRP的含量。结果 :(1)细菌感染组与病毒感染组、非感染性组比较PCT、CRP明显升高 ,差异有显著性 (P <0 0 1)。 (2 )病毒感染组与非感染组比较PCT、CRP轻度升高 ,无显著性差异 (P >0 0 5)。 (3 )细菌感染组治疗前后PCT、CRP比较有显著性差异。 (P <0 0 1)。结论 :新生儿感染时 ,PCT、CRP的检测有助于疾病早期的鉴别诊断 。
Objective:To study the change of serum procalcitonin (P CT) and C-reactive protein(CRP) in neonatal infection diseases and its clinical si gnificance.Methods:The contents of PCT and CRP in sera of 75 a nd 30 non-infected cases of newborn were examed.Results:(1)The levels of PCT and CRP in bacteria-infected group were significantly higher than that in virus-infected and non-infected groups (P<0 01).(2)The levels of PCT and CRP in virus-infected group were slightly higher than that in non-inf ected group and there was no significicant difference among them (P>0 05) 。(3)In the bacteria-infected group there were significant differences between the pretrearment levels of PCT and CRP and post-treatment levels of them.(P <0 01).Conclusion:The examination of serum PCT and CRP is helpful to make distinctive diagnosis for neonatal infections at early stage,and the dy namic determination of their level change is valuable for judgement of therapeut ic results.
出处
《医学理论与实践》
2003年第11期1254-1255,共2页
The Journal of Medical Theory and Practice
