摘要
目的探讨影响终末期糖尿病肾病血透效果的因素 ,为有效防治提供理论依据。方法选择 4 2例终末期糖尿病肾病 (DN)血透病人和同期 5 0例非糖尿病肾病 (非DN)血透病人 ,分别观察其存活时间、死亡原因、并发症及血生化指标。结果两组 1～ 2年 ,>2年存活时间差异有显著性意义 (P <0 .0 1,P <0 .0 5 ) ;主要死因为心血管病变 ,其次为感染 ;首次透析时肾功能与病死率成正比 ;DN组透析低血压、心血管病变、感染及视网膜病变较非DN组高 ,两组比较 ,差异有显著性意义 (P <0 .0 5 ,P <0 .0 1) ;两组血透前Glu ,血透期间Alb比较 ,差异有显著性意义 (P<0 .0 5 )。结论早期充分的血透、减少透析时血糖的波动、防治并发症、营养支持是减少终末期血透病死率 ,提高其存活时间及生活质量的有效措施。
Objective To evaluate the risk factors which influence the life quality and long-term survival of diabetic patients with end-stage renal disease (ESRD) during hemodialysis. Methods The total of ninty-two cases receiving hemodialysis were randomly divided into two groups: diabetic nephropathy group (DN group, n=42) and non-diabetic nephropathy group (non-DN group, n=50). During the hemodialysis, the survival time, causes of death, complications were observed and the blood biochemical parameters were measured in the two groups. Results There was significant difference in one-year survival time and two-year survival time between the two groups (P<0.01, P<0.05). The major causes of death were cardiovascular diseases, followed by infection. The mortality rate was related to the renal functions at initial hemodialysis. In addition, the incidence of cardiovascular diseases, intradialytic hypotension, infection in DN group was higher than in non-DN group (P<0.05, P<0.01). There was significant difference in Glu before hemodialysis and Alb during hemodialysis between the two groups (P< 0.05 ). Conclusion Effective hemodialysis at early stage, decreasing blood sugar fluctuation during hemodialysis, preventing and treating the complications and nutritional support can decrease the mortality rate for hemodialysis at end-stage and increase survival time and the quality of life.
出处
《护理学杂志（综合版）》
2003年第11期821-823,共3页
Journal of Nursing Science
关键词
糖尿病肾病
血液透析
相互影响分析
diabetic nephropathy
hemodialysis
interaction analysis
