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转录因子GATA-2的研究进展 被引量：3

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摘要 转录因子GATA - 2是具有锌指结构的GATA家族中的一员 ,它在造血系统中广泛表达 ,且与造血细胞的分化、发育关系密切 .GATA - 2主要调控造血干 /祖细胞的增殖和分化 ,亦可调控其他造血相关因子的表达 。
作者 吴秀丽 李扬秋
机构地区 暨南大学医学院血液病研究所
出处 《现代临床医学生物工程学杂志》 CAS 2003年第5期387-389,395,共4页 Journal of Modern Clinical Medical Bioengineering
基金 国家攀登计划资助项目 (95 -专 - 1 0 ) 国家自然科学基金 (3970 0 0 64) 广东省自然科学基金 (90 62 7) 国家教委留学回国人员启动基金 (教外司 [1 998] 679号 )
关键词 转录因子 GATA-2 造血细胞 造血调控 血液病
分类号 R346 [医药卫生—基础医学]
  • 相关文献

参考文献17

  • 1陈少华,李扬秋,杨力建,张洹.转录因子GATA-2基因在ANLL、CML和MDS中的表达[J].临床血液学杂志,2001,14(2):73-75. 被引量：4
  • 2李扬秋,汪明春.转录因子GATA-2在早期造血过程中的作用(英文)[J].中国实验血液学杂志,2000,8(1):66-70. 被引量：7
  • 3吴秀丽.造血转录因子GATA-3的研究进展[J].国外医学（输血及血液学分册）,2001,24(5):387-390. 被引量：4
  • 4Shinobu Tsuzuki ,Tariq Enver. Interactions of GATA - 2 with the promyelocytic leukemia zinc finger (PLZF) protein, its homologue FAZF, and the t(11,17) - generated PLZF - retinoic acid receptor alpha oncoprotein[J]. Blood, 2002, 99(9):3404.
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  • 10Ikonomi P, Noguchi CT, Miller W, et al. Levels of GATA - 1/GATA - 2 transcription factors modulate expression of embryonic and fetal hemoglobins [J]. Gene, 2000, 261(2):277.

二级参考文献25

  • 1李扬秋.转录因子GATA的发现及其在造血系统的研究进展[J].国外医学（输血及血液学分册）,1996,19(3):154-157. 被引量：5
  • 2李扬秋.－[J].中国实验血液学杂志,1999,7:182-182.
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  • 5OrfordRL,RobinsonC,HaydonJM,etal.ThematernalCCAATboxtranscriptionfactorwhichcontrolsGATA-2expressionisnovelanddevelopmentallyregulatedandcontainsadouble-stranded-RNA-bindingsubunit.MolCellBiol,1998;18:5557-5566
  • 6MinegishiN,OhtaJ,SuwabeN,etal.AlternativepromotersregulatetranscriptionofthemouseGATA-2gene.JBiolChem,1998;273:3625-3634
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共引文献11

同被引文献46

  • 1张耿,王赞,关宁,王学敏,李源,高洪文.中间偃麦草Na^+/H^+逆向转运蛋白的分子克隆及生物信息学分析[J].遗传,2007,29(10):1263-1270. 被引量：13
  • 2MORRISEY E E,IP H S,TANG Z,et al.GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily[J].Journal of Biological Chemistry,1997,272(13):8515-8524.
  • 3ONODERA K,YOMOGIDA K,SUWABE N,et al.Conserved structure,regulatory elements,and transcriptional regulation from the GATA-1 gene testis promoter[J].Journal of Biochemistry,1997,121 (2):251-263.
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  • 9Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome[J]. Blood, 2011, 118(10): 2653-2655.
  • 10Vinh DC, Patel SY, Uzel G, et al. Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia[J]. Blood, 2010, 115(8): 1519-1529.

引证文献3

二级引证文献7

现代临床医学生物工程学杂志
2003年 第5期

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