摘要
目的 :评价瑞易宁 (格列吡嗪控释片 )治疗 2型糖尿病的有效性和安全性。方法 :用瑞易宁治疗其它 2代磺脲类药物治疗失效者 31例 ,同时进行临床疗效及副作用的观察 ,观察时间为 8周。结果 :瑞易宁可明显降低空腹和餐后 2小时血糖、糖化血红蛋白 (P <0 0 1) ,提高餐后 2小时胰岛素水平 (P <0 0 5 ) ;有效率达 89% ,无明显肝肾功能不良反应。结论 :瑞易宁对其它 2代磺脲类药物失效者的治疗 。
Objective:To evaluate the efficiency and safety of control release glipizide of therapy on NIDDM.Methods:31 cases after failed treatment with other second generation of sulphonylureas were treated with control release gipizide for eight weeks,the clinical effect and side effect were observed.Results:Control release glipizide decreased FBG、2hPBG、HbAlc obviously,and increased 2hpINS level obviously;the effective rate was 89%,and no obvious liver or renal sideeffect were observed.Conclusion:Control release gipizide in treating the patients after unsuccessful treatmeat with second generation of sulphonylureas is effective and safe.
出处
《广西医学》
CAS
2003年第11期2116-2117,共2页
Guangxi Medical Journal
关键词
瑞易宁
治疗
2型糖尿病
临床观察
有效性
安全性
Non insulin dependent diabetes mellitus
Control release glipizide
Effeciency
Safety
