摘要
目的 探讨新生儿听力损失的影响因素。方法 对 82 6 2例新生儿听力筛查所得的 4 1例听力损失新生儿的资料进行基本特征的统计描述 ;采用以医院为基础的 1∶2配对的病例 对照研究方法 ,应用SAS6 .12软件进行单因素及多元条件Logistic逐步回归模型分析与新生儿听力损失有关的高危因素。结果 通过单因素分析 ,发现与新生儿听力损失有关的高危因素有 3个 :听力损失家族史 ,颅面畸形 ,新生儿重症监护 (NICU)史 ;条件Logistic逐步回归分析结果显示新生儿听力损失有两个独立的危险因素 :听力损失家族史 (OR =16 .94 5 ,95 %CI 1.2 1～ 2 37.36 9)和颅面畸形 (OR =6 70 3,95 %CI 0 .6 1～ 73.85 )。结论 听力损失家族史和颅面畸形是新生儿听力损失高危因素 ,应对其采取适当的干预措施。
Objective To explore the risk indicators of newborn hearing loss. Methods Statistic description was used to analyze the basic characteristics of 41 hearing loss infants screened from 8 262 newborns; one way analysis was used by 1∶2 matched case control study to analyze the risk indicators of newborns with hearing loss; chi-square test and multivariate condition Logistic stepwise regression mode were also used to find risk the indicators. Results By one way analysis, there were 3 high risk indicators associated with newborn hearing loss: family history of hearing loss, craniofacial anomalies, and NICU care history. By analysis of multivariate condition Logistic stepwise regression mode, family history of hearing loss( OR =16.945,95%CI 1.21-237.369) and craniofacial anomalies ( OR =6.703,95%CI 0.61-73.85)were 2 independent risk factors of newborn hearing loss. Conclusion Appropriate intervention measure should be done to reduce the high risk indicators that cause newborn hearing loss.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2003年第16期1399-1401,共3页
National Medical Journal of China
基金
国家自然科学基金资助项目 (3 0 10 0 2 0 7)
关键词
新生儿
听力损失
高危因素
研究
Hearing loss
Neonate
Newborn hearing screening
Risk indicators
Case control study
