摘要
目的:比较不同年龄阶段慢性萎缩性胃炎(CAG)患者各临床病理指标的差别,以期探讨各年龄段的患病特点。方法:按年龄将524例经病理活检证实的慢性萎缩性胃炎病例分为青年组(≤35岁)、中年组(36岁～59岁)和老年组(≥60岁)。比较不同年龄段患者的性别、病变部位、胃镜下表现、萎缩程度、肠上皮化生及幽门螺杆菌(Hp)感染情况等临床病理资料。结果:CAG以中老年多见(91.0％),青年组中患病女性多于男性(P<0.01),伴溃疡、息肉或结节状病变较中老年多见(P<0.05),而肠上皮化生率明显低于中老年组(P<0.01)。青年组和中年组萎缩程度明显低于老年组(P<0.01);各年龄组在病变部位、Hp感染方面无明显差异。结论:慢性萎缩性胃炎发病高峰年龄为40岁～60岁。青年患者中女性多见,以轻度萎缩及伴溃疡、息肉或结节状病变多见且多不伴肠上皮化生;中老年组则男性多见,以中度和重度萎缩多见且多伴有肠上皮化生。
Objective:To study the clinical and pathological features of chronic atrophic gastritis(CAG) at various ages. MethodsrThe patients were classified as follows:adolescent group(≤35 years),adult group(36 - 59 years),old -aged group(≥.60 years). All clinical and pathological features such as sex,location,endoscope trait.degree of atro-phy,intestinal metaplasia and Helicobacter pylori(Hp)status were recorded and compared. ResultsrMost CAG occured to the middle - aged patients(91. 0 %). The number of female patients were more than that of male in adolescent group(.P<0. 01). The prevalence rates of polyps or nodules in a background of CAG in youth were significantly high-er but the prevalence rates of intestinal metaplasia were significantly lower than those in middle -aged of atrophy in adolescent and adult groups subjects. The degrees were significantly lower than those in old-aged group. There were no statistical difference between the three groups about location and Hp status. Conclusion: The case peak of CAG was at the age of 40-60. Most female patients were found in youth and most of them had mild atrophy and concomitance changes such as ulcers or polyps or nodules and the prevalence rate of intestinal metaplasia was low. In middle-aged subjects ,the male patients were more than female patients and most of them had middle or severe atrophy and intestinal metaplasia.
出处
《临床医药实践》
2003年第10期730-731,共2页
Proceeding of Clinical Medicine
