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长效驱避剂的初步筛选研究 被引量:6

Preliminary Selective Studies on the Long Lasting Effect Repellant Formulations
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摘要 目的 研究一种对人有效保护时间 >8h ,且安全经济的长效驱避剂配方。方法 采用实验室 (GB T173 2 2 .10 -1998)和现场的药效测试方法对所配制的驱避剂配方进行效果测试。结果 实验室试验表明 ,以 2 0 %IR3 5 3 5配制 10、12、13、14号驱避剂配方在实验室内对白纹伊蚊的有效防护时间可达 8h以上 ;现场试验表明 ,10、12、13、14号驱避剂配方对人有效防止丘陵地区伊蚊的叮咬时间达 9h ,有效防止稻田地区中华按蚊的叮咬时间达 8h。结论以 2 0 %IR3 5 3 5与纤维素配制的驱避剂对人的有效保护时间可达 8h。纤维素对IR3 5 3 5有一定延长有效保护时间的缓释作用。实验所用配方对人的皮肤无不良反应 ,可作为户外活动人群防止蚊虫刺叮的驱避剂。 Objective To study and develop the Long lasting effect repellant formulations, safe and effective over 8 h. Methods The laboratory test method (GB/T17322.10-1998) and the field test method were used to evalue the effect of these repellant formulations made in laboratory on field. Results The protective time of 10,12,13,14 formulations with 20% IR3535 were all over 8 h against Aedes albopictus in laboratory. In field the protective time of the above formulations was up to 9 h against Aedes at weed site of hill and up to 8 h against Anopheles at cornfield in countryside.Conclusion The available protective time of formulations made of 20% IR3535 and cellulose was over 8 h. There was not negative impact when these formulations were utilized on human skin. We found the cellulose has control releasing role for IR3535. The mentioned formulations could be used for preventing people from mosquito biting outdoor.
出处 《中国媒介生物学及控制杂志》 CAS CSCD 2003年第5期358-359,共2页 Chinese Journal of Vector Biology and Control
关键词 驱避剂 蚊虫 有效防护时间 疟疾 登革热 Repellant Deet IR3535 Mosquito Available protective time
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参考文献3

  • 1.GB/T17322.10-1998.农药登记卫生用杀虫剂的室内药效评价.驱避剂[S].国家质量技术监督局,1998..
  • 2Fradin M.Comperative efficacy of insect repellents against mosquito bites[J].N Engl J Med , 2002,347:2-3.
  • 3Staub D. Effectiveness of a repellent containing DEET and EBAAP for preventing tick bites[J].Wilderness Environ Med ,2002,13:12- 20.

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