摘要
目的 探讨无肺部病变的婴幼儿肺功能残气量 (FRC)和肺炎婴幼儿FRC的改变。方法 对 36例无肺部病变的婴幼儿 (对照组 )和 2 5例肺炎婴幼儿 (肺炎组 ) ,采用超声流量仪和六氟化硫洗入洗出技术 ,取仰卧位时测量FRC。结果 肺炎婴幼儿FRC为 (9 6± 2 0 )mL/kg ,较对照组婴幼儿FRC(15 7± 3 9)mL/kg显著降低 (P<0 0 1) ;肺炎婴幼儿潮气量 (Vt)为 (6 3± 1 8)mL/kg ,较对照组婴幼儿Vt(8 5± 1 6 )mL/kg显著降低 (P <0 0 5 ) ;肺炎婴幼儿Vt/FRC比值 (0 6 6± 0 15 )与对照组婴幼儿Vt/FRC比值 (0 5 6± 0 12 )差异无显著性 (P >0 0 5 )。对照组婴幼儿FRC与身长、体重和年龄均呈正相关 ,相关系数分别为r =0 84 6、r =0 739和r =0 72 0(均P <0 0 1)。超声流量仪检测FRC的变异系数为 7 4 % (范围 0～ 2 6 % )。结论 肺炎婴幼儿FRC和Vt较无肺部病变婴幼儿均降低。无肺部病变婴幼儿FRC与身长、体重及年龄存在相关。
Objective To investigate the changes in functional residual capacity (FRC) in control (without pulmonary diseases) infants and in infants with pneumonia.Methods FRC was measured with ultrasonic flow meter and SF_6 washin/washout in 36 control infants undergoing surgical operation without pulmonary diseases and 25 with pneumonia.FRC was measured during spontaneous breathing and its values were obtained in triplicate with adequate time interval between each measurement to ensure re-equilibration to initial alveolar gas composition.Results Infants with pneumonia had significantly lower FRC than that of the control (9.6±2.0 vs 15.7±3.9 mL/kg,P<0.01).The same was true for tidal volume (Vt,6.3±1.8 vs 8.5±1.6mL/kg,P<0.05).There was no significance in Vt/FRC between the pneumonia and the control (0.6±0.15 vs 0.56±0.12,P>0.05).FRC was closely correlated to body length,weight or age in the control infants ( r=0.846,r=0.739 and r=0.720,respectively,P<0.01).The mean coefficient of variation of FRC was 7.4% (range 0～26%).Conclusion The FRC and Vt in infants with pneumonia are lower than that of the control infants.FRC is correlated with body length,weight and age in infants without pulmonary diseases.
出处
《中国实用儿科杂志》
CSCD
北大核心
2003年第10期615-617,共3页
Chinese Journal of Practical Pediatrics
