摘要
目的 :观察米索前列醇用于催产素引产失败未进入活跃期的剖宫产预防产后出血的效果。方法 :选择 80例剖宫产患者 ,均为催产素引产失败未进入活跃期的患者 ,随机分为米索前列醇组及催产素组。米索前列醇组 4 0例 ,术中打开腹膜时口服米索前列醇 4 0 0ug。催产素组 4 0例 ,胎儿娩出后宫体肌内注射催产素 2 0IU。以上各组观察术中及术后 2h内出血量。结果 :术中及术后 2h平均出血量 ,米索前列醇组为 2 18± 5 5 .4ml;催产素组 375± 6 4 .7ml。米索前列醇组与催产素组比较 ,差异有极显著性 (p <0 .0 1)。结论 :米索前列醇促进子宫收缩作用强于催产素 ,能较好地预防剖宫产术后出血 ,且用药方便、安全。
Objective:To observe the effects of Misoprostol on reduction of postpartum bleeding in the patients with failure of labor induction. Methods: 80 cesarean sections were randomized into two groups: Misoprostol group(n=40),400ug Misoprostol was given orally when peritoneum was incised; Oxytocin group (n=40),20IU oxytocin was injected into uterine muscle.The amount of bleeding within 2 hours after delivery was measured. Results: The mean amount of bleeding in Misoprostol group was 218±55.4 ml,in oxytocin group was 375±64.7 ml.The difference was significant p<0.01.Conclusion: Misoprostol is more effective in reduction of postpartum bleeding than that of oxytocin.
出处
《河北医学》
CAS
2003年第9期806-807,共2页
Hebei Medicine