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围产期心肌病的临床特征和处理

The clinical features and medical management of peripartum cardiomyopathy
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摘要 目的 :探讨围产期心肌病 (peripartumcardiomyopathy)的临床特征及其内科处理问题。方法 :总结分析11例围产期心肌病的发病特点、临床表现、心电图及胸部X线检查、超声心动图改变和治疗方法与转归。结果 :本组均有不同程度的左、右心衰竭表现 ,心功能 (NYHA分级 )Ⅲ级 7例、Ⅳ级 4例。心电图多表现为窦速和左室肥厚 ,X线检查心胸比率平均 0 .61± 0 .0 7。平均左室射血分数 0 .3 2± 0 .16。治愈出院 10例 ,1例因体循环多发性栓塞死亡。结论 :围产期心肌病相对少见 ,但心衰程度较重。在常规应用洋地黄、利尿剂和ACEI的基础上 ,应加用 β阻滞剂治疗。同时应注意抗凝 。 Objective: To investigate the clinical features and medical management of peripartum cardiomyopathy.Methods: 11 cases were analyzed by their clinical manifestations,changes of ECG,chest roentgenography and echocardiogram,therapeutic methods and outcomes.Results: All patients had varying degrees of left and right heart failure,NYHA cardiac function classification:classⅢ was 7 cases and classⅣ was 4 cases.Most patients had sinus tachycardias and left ventricular hypertrophy on ECG.Averaged heart/chest ratio on roentgenogram was 0.61±0.07.Averaged left ventricular ejection fraction was 0.32±0.16.Ten patients were cured to discharge,one patient died of multiple systemic embolisms.Conclusion: Peripartum cardiomyopathy is a disease of relatively uncommon but with advanced heart failure.β_blockers should be added to conventional therapies including digitalis,diuretics and angiotensin_converting enzyme inhibitors.Anticoagulation also should be attentioned to prevent complications of embolization.
作者 梁智斌
出处 《河南医学研究》 CAS 2003年第3期268-269,共2页 Henan Medical Research
关键词 围产期心肌病 临床特征 心电图 影像学检查 血栓栓塞 心力衰竭 药物治疗 peripartum cardiomyopathy clinical features heart failure medical therapy
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