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肺动脉瓣口多普勒频谱分析与肺循环血流动力学的定量关系——与有创检查同步对比研究

RELATION OF PULMONARY FLOW VELOCITY PATTERNS TO HEMODYNAMICS OF PULMONARY CIRCULATION:A SIMULTANEOUS STUDY OF PULSED DOPPLER AND CATHETERIZATION
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摘要 同步测定了42例患者的肺动脉瓣口前向脉冲多普勒频谱和心导管肺循环血流动力学的指标。结果:1.肺动脉收缩压(PASP)、肺血管阻力(PVR)与AT,AT/RVET、AV/DV的r值为|0.72~0.78|,P<0.01。肺循环血量(QP)与这3项频谱指标的r值分别为0.47,0.29和-0.31、P分别为<0.01,>0.05和<0.05,相关方向与之PASP和PVR的相反。2.多元逐步回归分析示PASP、PVR与AT,AT/RVET及AV/DV的复r值分别为0.80,0.81,0.78(P均<0.001)。QP因素的影响方向略相反,但不显著。3.脉冲多普勒频谱分析各单因素在PASP正常组与升高组均数间差异有显著意义,但有较多病例重叠。结论是肺动脉瓣口脉冲多普勒指标变化系肺循环血流动力学多变量的综合作用,以PASP和PVR为著,用各指标估测肺动脉压力时,应考虑PVR和QP等变量的影响,以提高诊断符合率。 In order to assess relation of pulmonary flow velocity patterns derived bY pulsed Doppler to pulmonary hemodynamics derived from catheter-ization,42 patients were measured simultaneously by these two techniques. The results showed:1.with liner regression,the good correlativities of pulmo-nary arterial systolic pressure(PASP),pulmonary vascular resistance(PVR) with accelarated time(AT),AT/right ventricular ejection time(AT/RVET), and accelaration/deccelaration(AV/DV)were found respectively(r=|0.72-0.78|,P<0.01).The correlativities of pulmonary flow(QP)with AT,AT/RVET and AV/DV were not very good(r=0.47,0.29,-0.39,P<0.01,>0.05,<0.05 respectively).2.multiple stepwise regression analysis revealed that AT,AT/RVET and AV/DV could be quantitatively estimated with two hemodynamic variants—PASP,PVR and its coefficients of multiple correlation were 0.80,0.81 and 0.78(<0.01).The correlative direction of QP was adverse to that of PASP and PVR but its F value was not significant.We concluded that changes of pulmonary flow velocity patterns were caused by multiple pulmonary hemodynamic variants in which PASP and PVR were very important factors.When we estimate PASP with pulsed Doppler echo-cardiography,we should also consider the influence of PVR and QP so as to improve diagnostic ability of the technique.
出处 《山东医科大学学报》 1992年第1期54-57,共4页 Acta Academiae Medicinae Shandong
关键词 肺动脉压 肺循环血量 超声心动图 Echocardiography Pulmonary arterial pressure Pulmonary vascular resistance
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