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复方免疫活性因子对新城疫疫苗免疫增强作用的研究

Study On the Immune Active Factor Strengthening the Action of Newcastle Disease Vaccine
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摘要 本研究对健康雏鸡7日龄免疫前12小时按照分组分别使用免疫活性因子和生理盐水,然后以新城疫Ⅳ系弱毒苗点眼滴鼻,分别在新城疫Ⅳ系冻干苗免疫后7、14、21d,心脏采血,采用HI法检测新城疫抗体水平。结果表明,应用免疫活性因子及新城疫疫苗后各试验组7d抗体水平明显升高,14及21d抗体水平大大高于单用ND疫苗组,经t值检验,试验组与对照组组间差异显著(P<0.05)熏试验组间差异不显著(P>0.05)。研究结果提示免疫活性因子是一种很有前途的生物免疫增强剂。 The healthy chicken were done with compound immunity active factor and physiological saline at7th age12hours before they were inoculated Newcastle Disease vaccine through nostril and eye.At the7th,14th and21th day after inoculation,the blood samples were taken from heart and antibody level were detected by hemagglutination Inhibition test.The results show that the antibody level rise remarkably in compound active factor groups at7th day,and the antibody level rise significantly at14th and21th day than the control groups.By t-value test,experiment group and control groups differ remarkably(P<0.05),while the difference between experiment groups are not remarkable(P>0.05).So we conclude that compound immunity active factor is one of excellent immunoadjuvants.
出处 《山东家禽》 2003年第10期8-9,共2页 Shandong Poultry
关键词 复方免疫活性因子 新城疫 疫苗 免疫增强作用 雏鸡 生理盐水 冻干苗免疫 心脏采血 抗体水平 compound immunity active factor Newcastle Diseae vaccine immunity-strengthen
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