1Gomez-Navarro J,Contreras JL,Arafat W,et al.Genetically modified CD34 + cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model[J]. Gene Ther,2000,7(1) :43 - 52.
2Ararat WO,Casado E, Wang M,et al. Genetically modified CD34 + cells exert a cytotoxic byztander effect on human endothelial and cancer cells[J] . Clin Cancer Res, 2000,6 (11) : 4442 - 4448.
3Lyden D,Hattori K,Dias S, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth [J]. Nat Med,2001,7(ll) :1194 - 1201.
4Bolontrade MF,Zhou RR,Kleinerman ES. Vasculogenesis Plays a Role in the Growth of Ewing's Sarcoma in Vivo[ J ]. Clin Cancer Res, 2002,8 ( 11 ) : 3622 - 3677.
5Reyes M, Dudek A, Jahagirdar B, et al. Origin of endothelial progenitors in human postnatal bone marrow [J]. J Clin Invest ,2002,109(3) : 337 - 346.
6Lyden D, Young AZ, Zagzag D, et al. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts [ J ]. Nature, 1999, 401(6754): 670 - 677.
7Folkman J. Can mosaic tumor vessels facilitate molecular diagnosis of cancer[J]. Proc Natl Acad Sei U S A,2001,98(2) :398 - 400.
8Holash J, Maisonpierre PC, Compton D, et al. Vessel cooption,regression,and growth in tumors mediated by angiopoietins and VEGF[ J ]. Science, 1999,284 (5422) :1994 - 1998.
9Holash J, Wiegand SJ, Yancopoulos GD. New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF[J ]. Oncogene, 1999,18(38) :5356 - 5362.
10Yancopoulos GD, Davis S, Gale NW, et al. Vascular-specific growth factors and blood vessel formation[J]. Nature,2000,407(6801) -242 - 248.
3DAVIS S,GALE NW,ALDRICH TH,et al.Ligands for EPH-related rece-ptor tyrosine kinases that require membrane attachment or clustering for activity[J].Science,1994,266(5):816-819.
4WALKER-DALS J,HESS AR,HENDRIX M,et al.Differential regulation of EphA2 in normal and malignant cells[J].Am J Pathol,2003,162(4):1037-1042.
5KATAOKA H,IGARASHI H,KANAMORI M,et al.Correlation of EPHA2 over expression with high microvessel count in human primary colorectal Cancer[J].Sci,2004,95(2):136-141.
6STEIN E,LANE AA,CERRETTI DP,et al.Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes,attachment and assembly responses[J].Genes Dev,1998,12(4):667-678.
7BRANTLEY DM,CHEN N,THOMPSON E,et al.Soluble EphA2 receptors inhibit tumor angiogenesis and progression in vivo[J].Oncogene,2002,21(46):7011-7026.
8FANG WB,BRANTLEY-SIEDERS DM,PARKER MA,et al.A Kinase-depedent role for Epha2 receptor in promoting tumor growth and metastasis[J].Oncogene,2005,24(53):7859-7868.
9NAKAMURA R,KATAOKA H,SATO N,et al.EPHA2/EFNA1 expression in human gastric Cancer[J].Sci,2005,96(1):42-47.
10Popov Y,Schuppan D.Targeting liver fibrosis:strategies for development and validation of antifibrotic therapies.Hepatology.2009; 50(4):1294-1306.