摘要
从西藏传统发酵乳(西藏灵菇)中分离筛选到1株高效降胆固醇乳酸菌KM-16。应用VITEK-32全自动微生物分析系统鉴定该菌为干酪乳杆菌(Lactobacillus casei)。在液体培养基中KM-16乳酸菌对降胆固醇达51.8%。用KM-166灌胃高脂血症模型小鼠研究其对血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)的影响。结果表明灌胃14d后,实验组小鼠血清中TC、TG浓度较对照组显著降低(p<0.01),同时HDL-C浓度有所增加,动脉硬化指数(AI)低于对照的水平。
Cholesterol-degrading strains KM-16 was isolated from Tibet traditional koumiss.Using VITEK-32 AutomaticMicrobe Analytic Systems,the isolate was identified as lactobacillus casei.In MRS medium,KM-16 strain showed 51.8% ofcholesterol was degraded.The cholesterol-degrading activities of the strains were mainly due to their bile salt coprecipitionactivity and the cholesterol asimilation.The effects of KM-16 on the total serum cholesterol(TC),triglycerids(TG) and high densitycholesterol(HDL-C)were investigated in artificially-induced hyperlipemial mice.The results showed that the mean values for TCand TG concentrations decreased significantly after feeding 14d while HDL-C in serum increased at the same time.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2003年第10期142-145,共4页
Food Science
基金
江苏高技术研究发展计划(BJ2002322)
国家(863)高技术研究发展计划(2002AA248041)
