摘要
目的 探讨流行性出血热 (EHF)患者 N-乙酰 -β- D氨基葡萄糖苷酶 (NAG)在各期中的变化及其与EHF病程的相互关系。方法 采用比色法对 86例 EHF患者尿 NAG酶活性指数进行测定。结果 除恢复期外 ,各期 EHF患者尿 NAG酶活性指数均明显高于对照组 (P <0 .0 1) ,并以休克期、少尿期、多尿期最为显著 (P <0 .0 0 1)。结论 尿 NAG酶活性指数与 EHF患者肾损伤程度呈显著正相关 (r=0 .89,P <0 .0 1) ,其检测有助于EHF的早期诊断。
Objective To study the internal relationship between the alterations of β N acetyl glucosamdase (NAG) in urine and the courses of the patients suffering from epidemic hemorrhagic fever (EHF).Methods The active coefficient of NAG in the urine of 86 patients suffering from EHF were determined with colorimetric method.Results The active coefficients of NAG in urine of the patients with EHF in fever,shock,polyuria and oliguric stages were significantly higher than those in the control group and in the convalescent (P<0.01).Conclusions The extent of changes of active coefficient of NAG in urine is positively correlated to the extent of injured of kidneys of the patients with EHF.The active coefficients of NAG determined at proper time could be useful to make diagnosis therapy and prognosis.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2003年第5期448-449,共2页
Chinese Jouranl of Endemiology
