摘要
目的 :探讨前列腺特异性抗原 (ProstateSPecificAntigen .psa)在临床中的应用及本地区的正常参考值。方法 :用ELISA双抗体夹心法检测 15例前列腺癌、2 5例良性前列增生患者血PSA浓度并与 6 0例健康人作比较。结果 :前列腺癌 (PorstateCancer,CaP)组病人血清PSA为 38.15± 2 9.76 (X±Sng/ml下同 ) ;良性前列腺增生 (BenignProstateHyperplasia ,BPH)组为 6 .2 8± 5 .2 0 ;健康对照组为 2 .75±1.0 2 ,三者之间均有显著性差异 (P <0 .0 1)。将PSA值与年龄作相关分析 ,得r=0 .5 2 ,P <0 .0 1。结论 :血清PSA可作为诊断和鉴别前列腺增生和良性前列腺癌增生的一个很有价值的指标 ,本地区正常男性以PSA≤ 4ng/ml为正常参考值 ,但在分析 6 0岁以上的老年人时 。
Objective: To explore the role of prostate specific antigen(PSA) in clinic and the lical normal reference value. Method: Datected the serum PSA concentration of 15 patients with prostate cancer and 25 patients with benign prostatic hyperplasia comqaring with 60 health persons by ELISA Double Antiboies Sandwith. Results: The serum PSA concentration in patient with prostate cancer was 38.15±29.76(±s,mg/ml,the below as the asme),that in patient with benign prostatic hyperplasia was 6.28±5.20,that in health person was 2.75±1.02. There were significant fifferences among the three groups(P<0.01). Correlation: analysis was performed betowwn PSA concentration and age, r=0.52,P<0.01. Conclusion: The serum PSA was a very valuable marker in diagnosing and distinguish from prostate canccer and benign prostatic hyperplasia. PSA≤4ng/ml was difined as normal reference value in health male of this area. But the normal reference value should be raisd properly with we analyse the man over sixty.
出处
《河北医学》
CAS
2002年第4期323-325,共3页
Hebei Medicine
