摘要
目的 :采用微剂量肝素治疗危重患儿DIC ,评价其疗效。方法 :将 4 4例危重症并发DIC患儿作为研究对象 ,按肝素治疗剂量不同随机分为 2组 ,微剂量肝素组 2 3例 ,常规剂量肝素组 2 1例。微剂量肝素组在确诊DIC情况下 ,应用肝素 10 μ/kg .hr,稀释后持续静脉滴注 ,常规剂量组在确诊DIC后应用肝素 6 0～ 12 5 μ/kg ,每 4～ 8h静脉点滴或皮下注射。两组其他治疗原则相同 ,观察两组治愈率。结果 :微剂量肝素组死亡率较常规治疗组明显下降P <0 .0 5 ,两组具有显著性差异。结论 :微剂量肝素治疗DIC是一项行之有效的临床措施 。
Objective: Use mini dose heparin to treat DIC in critically ill children and evaluate its curative effect. Method: Using 44 DIC cases in critically ill children, randomly divide the patients into two groups, 23 cases as one group using mini dose heparin, 21 cases as another group using normal dose heparin. The mini dose heparin group, having been accurately diagnosed as DIC, was given intravenous injection using diluted heparin 10 /kg.hr; The normal dose heparin group , having been accurately diagnosed as DIC , was given intravenous injection or subcutaneous injection every 4～8 hours, using heparin 60～125u/kg. All other treatment conditions were the same for the two groups . Observed the cure rate . Results: The death rate for the mini dose heparin group was significant lower (p< 0.05) , compared to the normal dose heparin group . The effects of the two groups were evidently different. Conclusion:Using mini dose heparin to cure DIC is an effective clinical measure , using mini dose heparin to cure DIC is safe and effective.
出处
《河北医学》
CAS
2002年第4期292-294,共3页
Hebei Medicine
