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高同型半胱氨酸血症与冠心病

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摘要 同型半胱氨酸是蛋氨酸和半胱氨酸代谢过程中一个重要的中间产物。研究发现血液中同型半胱氨酸增高,即高同型半胱氨酸血症,能够导致血管内皮损害,促进低密度脂蛋白的氧化、血小板集聚及血管平滑肌细胞增殖,从而促发动脉粥样硬化的发生。人们已经逐渐认识到它是引起心脑血管意外的独立危险因素。近年来,高同型半胱氨酸血症与冠心病,尤其是急性冠状动脉综合征的研究越来越多,然而,结果并非完全一致。遗传和环境两方面的因素共同决定了血浆同型半胱氨酸的水平,补充B族维生素可以降低血浆同型半胱氨酸的水平。
出处 《国外医学(老年医学分册)》 2003年第5期205-209,共5页 Foreign Medical Sciences(Geriatrics)
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