摘要
目的 评价增加饮水量对泌尿系结石及其复发的预防效果。方法 确定资料检索范围(即Medline,Embase,Cochrane临床对照试验资料库及中国生物医学文摘数据库)并设计检索策略,通过机检和手检获取符合纳入标准的文献,并且由两位研究者独立评估试验质量和提取数据。结果 共4个研究符合纳入标准,其中1篇为随机对照试验,1篇为临床对照试验,2篇为前瞻性队列研究。Meta-分析的结果表明,增加饮水量预防泌尿系结石的OR合并及95％可信区间分别为0.64和0.53-0.77,具有统计学意义;增加饮水量预防泌尿系结石复发的OR台并及95％可信区间分别为0.56和0.37-0.84,具有统计学意义;增加饮水量可以延长泌尿系结石的复发间隔时间,具有统计学意义(P=0.016)。结论 增加饮水量可预防泌尿系结石及其复发,并能延长泌尿系结石的复发间隔时间。
Objective To assess the effectiveness of increasing water intake for the prevention of urinary calculi and its recurrence. Methods We defined the searching area, which included Medline, Embase, Cochrane CCTR and CBMA, and found the relevant materials by computer search and document search. At least two reviewers assessed trials quality and extracted data independently. Results A total of 4 studies met the inclusion criteria ( 1 RCT, 1 CCT and 2 prospective cohort studies). Mela-analysis' results showed that the aggregate OR and 95%CI of the effect of increasing water intake for the prevention of urinary calculi were 0.64 and 0.53-0.77;the aggregate OR and 95%CI of the effect of increasing water intake for the prevention of recurrence were 0.56and 0.37-0.84;increasing water intake can prolong the recurrence interval(P=0.016).Each result had statistical significance. Conclusion Increasing water intake can prevent urinary calculi and its recurrence. Increasing water intake can prolong the recurrence interval.
出处
《中国循证医学杂志》
CSCD
2003年第3期181-185,共5页
Chinese Journal of Evidence-based Medicine
基金
纽约中华医学会循证医学项目基金
