摘要
目的:探讨40岁以下青年人肺癌临床及病理学特征是否不同于中老年人肺癌。方法:对1995年1月至2000年12月收治的125例40岁以下青年人肺癌(青年组)以及随机选择的138例40岁以上(包括40岁)的中老年人肺癌(中老年组)进行回顾性分析,比较两组临床病理特征。结果:与中老年组相比,青年组中女性多(P<0.05),平均症状持续时间长(P<0.001),误诊率高(P<0.001)及平均误诊时间长(P<0.001),腺癌为主要病理类型(P<0.001),癌细胞分化差(P<0.001),就诊时晚期多(P<0.001),接受综合治疗比例多(P<0.001),两组中家族史和吸烟史无统计学意义。结论:青年人肺癌的临床和病理学特征明显不同于中老年人肺癌,提高对青年人肺癌的认识有临床实际意义。
Objective:To analyse the different clinic al and pathological features between young pul-monary carcinoma patients under40years of age(<40)and middle-and-old-aged ones(≥40).Methods:The clinical and pathological features of125young pulmonary carcinoma patients and138middle-and-old-aged patients were comparied.Results:Comparied with the middle-and-old-aged group,the young group had more female cases(P<0.05),longer duration of symptoms (P<0.001),higher rate of misdiagnosis(P<0.001)and longer time of misdiagnosis(P<0.001).Adenocarcinoma was the main pathological type(55%)in young group.In addition,the young group had the poorer differenciation of cancer cells(P<0.001),higher percentages of advanced lung cancer(P<0.001)and received more complex treatment (P<0.001).There were no distinct differences of family history and smoking history in the two groups.Con clu sion:The clinical and pathological features of young pulmonary carcinoma patients are quite different from those of middle-and-old-aged ones.It has practically clinical significance to furtherly understand young pulmonary carcino-ma cases.
出处
《山东大学学报（医学版）》
CAS
2003年第4期430-431,434,共3页
Journal of Shandong University:Health Sciences
