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Melatonin的脑保护机制研究进展

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摘要 Melatonin(MT)是松果体分泌的一种神经内分泌激素,它不仅参与生物周期性节律、神经-内分泌-免疫调节、镇静、催眠等,而且在脑缺血、Alzheimer病、癫痫、失眠等多种脑部疾病中具有保护作用。目前发现清除自由基、调节中枢神经递质、调节细胞膜离子通透性、抑制神经元凋亡等是MT脑保护的主要机制。
出处 《国外医学(神经病学.神经外科学分册)》 2003年第4期330-332,共3页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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  • 1Joseph R. Lakowicz,Henryk Szmacinski,Michael L. Johnson.Calcium imaging using fluorescence lifetimes and long-wavelength probes[J]. Journal of Fluorescence . 1992 (1)
  • 2Choi DW,Maulacci-Gedde M,Kriegstein AR.Glutamate neurotoxicity in cortical cell culture. The Journal of Neuroscience . 1987
  • 3Choi DW.Glutamate neurotoxicity and diseases of the nervous system. Neuron . 1988
  • 4Clapham DE.Calcium signaling. Cell . 1995
  • 5Williamson JR,Monck JR.Hormone effects on cellular Ca2+fluxes. Annual Review of Physiology . 1989
  • 6Reiter RJ.Oxidative damage in the central nervous system:protection by melatonin. Progress in Neurobiology . 1998
  • 7Pierpaoli W,Regelson W.Pineal control of aging: effect of melatonin and pineal grafting on aging mice. Proceedings of the National Academy of Sciences of the United States of America . 1994
  • 8Lechleiter JD,Clapham DE.Molecular mechanisms of intracellular calcium excitability in X laevis oocytes. Cell . 1992
  • 9Pappolla MA,Sos M,Omar RA,et al.Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. The Journal of Neuroscience . 1997
  • 10Vanecek J,Klein CD.Melatonin inhibits gonadotropinreleasing hormone-induced elevation of intracellular Ca2+ in neonatal rat pituitary cells. The Journal of Endocrinology . 1992

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