摘要
采用大鼠 8周递增负荷游泳训练模型 ,观察不同运动负荷方式对大鼠心脏超微结构的影响 ,以及血浆和心肌中舒血管因子一氧化氮NO、一氧化氮合酶NOS的变化 ,探讨不同运动负荷对大鼠的影响 ,并对其产生机制进行初步探讨。研究结果表明有氧训练能够使心肌的超微结构改善 ,提高心肌的cNOS活性、血浆NO水平 ,促进内皮组织舒张反应 ;大强度长时间的训练使心肌微细损伤出现 ,内皮组织损伤 ,但血浆NO水平变化不大。
To explore effects of exercise on myocardial ultrastructure, plasma NO and NOS and discuss the action mechanism involved, a 8-week incremental swimming model is carried out in rats. The results show that aerboic training results in significantly improving myocardial ultrastructure, myocardial local cNOS activity and plasma NO concentration, which facilitates endothelial dilation response. Meanwhile heavy intensity swimming leads to myocardial ultrastructure destruction and endothelial tissue damage with no significant change in plasma NO conceneration.
出处
《沈阳体育学院学报》
2003年第3期38-40,49,共4页
Journal of Shenyang Sport University
关键词
运动负荷
NO
NOS
超微结构
运动性心脏
exercise loads
myocardial hypertrophy
electric microscope rat
NO
NOS
