摘要
目的 比较速眠新与盐酸氯胺酮和速眠新复合麻醉对猕猴的麻醉效果。方法 成年健康猕猴 10只 ,动物分成单纯麻醉组 (速眠新组 ,5只 )和复合麻醉组 (速眠新和盐酸氯胺酮组 ,5只 ) ,均采用肌内注射麻醉。结果 速眠新麻醉维持时间仅 0～ 1h ,麻醉效果低于复合麻醉效果。速眠新有较好的镇静、镇痛和肌肉松弛作用 ,复合麻醉使速眠新效果更佳 ,麻醉时间更长、更稳定 (1～ 2h) ,复苏期较快。结论 速眠新和盐酸氯胺酮复合麻醉适合动物实验时间较长的手术 。
Objective To compare the anesthetic efficacy of Sumianxinzhusheye and Sumianxinzhusheye combined with ketamine hydrochloride injection on rhesus monkeys. Methods Ten healthy rhesus monkeys were included in the present study. Animals underwent muscular injection of anesthetics were divided into two groups:%Sumianxinzhusheye% anesthesia (n=5) and %Sumianxinzhusheye% combined with ketamine hydrochloride anesthesia(n=5). Results It was found that the anesthetic effect of Sumianxinzhusheye combined with ketamine hydrochloride was superior to Sumianxinzhusheye alone(0～1h).Although Sumianxinzhusheye anesthesia revealed well response for sedation, analgesia, as well as muscular relaxation, the combined anesthetization could improve the effect of Sumianxinzhusheye treatment, showing prolonged(1～2h) and stable anesthesia together with quick resuscitation.Conclusion Sumianxinzhusheye combined with ketamine hydrochloride anesthesia appearsto be a satisfacitory method for rhesus monkeys with prolonged operation.
出处
《中国实验动物学报》
CAS
CSCD
2003年第3期191-192,共2页
Acta Laboratorium Animalis Scientia Sinica
关键词
速眠新
盐酸氯胺酮
猕猴
麻醉效果
Ketamine
Sumianxinzhusheye
Anesthesia
Macaca Mulatta
