摘要
①目的 探讨血清心肌肌钙蛋白I(cTnI)在心肌梗死病人发病后不同时间的诊断价值。②方法 采用OpusTM全自动急诊干式免疫分析仪定量法 ,检测了 80例AMI病人的动态血清cTnI及肌酸激酶同工酶 (CK MB)活性。③结果 80例AMI病人cTnI总阳性率为 97.5 0 % ,阳性率在发病后 4h内达 4 5 .0 0 % ,7d时仍高达33.75 %。AMI病人发病 2 4h后心肌cTnI较CK MB的阳性率明显增高 (χ2 =9.0 14～ 4 7.6 19,P <0 .0 1)。④结论AMI病人心肌cTnI检测阳性出现时间早、持续时间长 ,是一种高度灵敏。
Objective To evaluate the diagnostic value of dynamic changes of cardiac troponin I (cTnI) in serum for patients with acute myocardial infarction(AMI) in different duration. Methods Automatic dry immunologic analyzer was used, serum cTnI and CK-MB were detected in 80 patients with AMI. Results The sensitivity of cTnI was 97.50%. Four hours and seven days after the attack, the positive rates were 45.00% and 33.75%, respectively. Twenty-four hours after the attack, the positive rate of cTnI was higher than that of CK-MB (χ 2=9.014-47.619,P<0.01). Conclusion cTnI appears early in serum in patients with AMI and lasts for long duration. It is a marker with high sensitivity and specificity for myocardial injury.
出处
《齐鲁医学杂志》
2003年第3期258-259,共2页
Medical Journal of Qilu
