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美托洛尔治疗充血性心力衰竭效果观察 被引量:1

METOPROLOL FOR CONGESTIVE HEART FAILURE: A CLINICAL OBSERVATION OF ITS OUTCOME
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摘要 ①目的 观察美托洛尔治疗充血性心力衰竭的效果。②方法  88例心功能Ⅱ~Ⅲ级住院充血性心力衰竭病人 ,随机分为美托洛尔治疗组 (4 8例 )及对照组 (4 0例 )。对照组给予常规治疗 ;治疗组在常规治疗基础上加用美托洛尔 6 .2 5~ 2 5 .0 0mg/d ,疗程 4周。③结果 治疗 4周后 ,治疗组疗效明显优于对照组 (uc=2 .17,P <0 .0 5 )。④结论 在常规抗心衰治疗基础上加用美托洛尔 ,是一种安全、有效的临床治疗方法。 Objective\ To study the clinical effects of metoprolol for congestive heart failure. \ Methods\ Eighty eight inpatients with congestive heart failure (cardiac function NYHA Ⅱ-Ⅲ class) were divided randomly into two groups: treatment group (48 cases) and control group (40 cases). The routine therapy for the two groups was same , the only difference was that for the treatment group, metoprolol, 6.25-25.00 mg/d, was added. The course was four weeks for both groups.\ Results\ After four week treatment, the total outcome of the treatment group was markedly superior to the control group ( u c=2.17,P <0.05). Conclusion\ Metoprolol is an effective medicine for congestive heart failure on the basis of routine therapy.
出处 《青岛大学医学院学报》 CAS 2003年第3期343-344,共2页 Acta Academiae Medicinae Qingdao Universitatis
关键词 充血性心力衰竭 美托洛尔 治疗 效果观察 心电图 X线胸片 超声心动图 heart failure, congestive metoprolol treatment outcome
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  • 1[1]Waagstein F,Hjalmarson A,Varnauskas E, et al. Effects of chronic beta-adrenogic receptor blockade in congestive cardiomyopathy[J]. Br Heart J,1975,37:1022.
  • 2[2]Paker M.The heart hormonal hypothesis a theory to explain the mechanism of disease progression in heart failure[J]. JAMA Cardiol,1992,20(1):248.
  • 3[3]MERIT-HF Study Group. Effect of metoprolol CR/XL in chronic heart failure: metoprolol CR/XL randomized intervention trial in congestive heart failure (MERIT-HF)[J]. Lancet,1999,353(9169):2001.

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