摘要
目的 探讨 IL - 12与老年人肺结核发病之间的关系。方法 对 38例新登记涂阳老年肺结核病人 ,34例青壮年肺结核及 2 7例健康老人及 5 0例健康青壮年的血浆 IL - 12进行了检测与分析。结果 老年肺结核组及青壮肺结核组的血浆内 IL - 12水平较正常组降低 ,老年肺结核组降低更为明显 (P<0 .0 5 )。结论 监测老年肺结核病人体内 IL - 12水平对结核病的发生、发展和预后都有一定意义。
Objective To observe interleukin 12 level in the elderly patients with active pulmonary tuberculosis.Methods Using double antiboby sandwich ELISA method, IL 12 level was measured in the plasma obtained from 38 aged patients with active pulmonary tuberculosis, 34 younger patients, and 77 healthy individuals as controls. Results It was found that the IL 12 level in the two TB groups was lower than those in the healthy control group. There were significant differences between patients and controls (P<0.1), and between the aged and the young groups (P<0.05).Conclusion IL 12 is an essential measure for the onset and development of tuberculosis, especially for the elderly patients.
出处
《临床肺科杂志》
2003年第5期409-410,共2页
Journal of Clinical Pulmonary Medicine
关键词
老年人肺结核
白介素—12
Tuberculosis Elderly Interleukin 12 (IL 12)
