摘要
对有关姜黄素代谢研究的国内外文献进行了归纳和分析。姜黄素的血药浓度低 ,生物利用度不高 ;姜黄素在体内的生物转化包括还原 ,与葡萄糖醛酸结合。姜黄素的吸收机制。
The serum concentration of curcumin is low. The poor bioavailability of curcumin is due to its rapid metabolism. The biotransformation of curcumin through reduction and glucuronidation in vivo was suggested. Further study to elucidate the absorption mechanism of curcumin and the relationship between metabolites and bioactivity are needed.
出处
《中国药理学通报》
CAS
CSCD
北大核心
2003年第10期1097-1101,共5页
Chinese Pharmacological Bulletin
基金
中国抗癌协会太极抗癌科学基金资助项目(2 0 0 0年度 )
关键词
姜黄素
代谢
curcumin
metabolism