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二尖瓣主动脉瓣三尖瓣同时置换治疗重症风湿性瓣膜病 被引量:9

Mitral, aortic and tricuspid valve replacement for severe rheumatic disease
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摘要 目的 总结二尖瓣主动脉瓣三尖瓣同期置换治疗重症风湿性心脏瓣膜病的手术疗效。方法  1999年 6月至 2 0 0 1年 6月 94 1例病人进行瓣膜置换术 ,其中 2 4例同期进行二尖瓣、三尖瓣和主动脉瓣置换 ,占瓣膜置换病人的 2 5 5 %。 2 4例病人中女 17例 ,男 7例 ;年龄 18~ 5 9岁 ,平均 36岁 ;体重 37~ 5 6kg。其中 8例曾行二尖瓣闭式扩张术、11例合并左房血栓、16例病人合并有肝肿大 (肋下 2~ 8cm)和下肢水肿、8例合并有腹水。X线胸片示心胸比率为 0 6 6~ 0 91。超声检查示三尖瓣均有严重反流 ,反流面积为 4 2~ 34 0cm2 ,平均 (16 8± 9 3)cm2 。术前心功能III级 9例 ,VI级 15例。 6例病人因药物不能控制心衰而行急诊换瓣手术。结果 死亡 1例 ,死亡率为 4 2 %。术后 1周、3、6个月复查超声心动图示各心腔内径较术前明显缩小。出院者均得到随访 ,随访时间 2 0~ 36个月 ,平均 2 6 4个月。术后心功能I~II级2 0例 ,III级 4例。术后 3~ 12个月复查超声心动图未见机械瓣功能障碍及血栓形成。结论 对于联合瓣膜病变 ,三尖瓣有严重器质性病变的病人 ,在进行二尖瓣主动脉瓣置换的同时进行三尖瓣置换 ,有利于术后右心功能的恢复 ,能更好地改善心脏的血流动力学特性 ,改善心功能 。 Objective: To evaluate the mitral, aortic and tricuspid valve replacement for rheumatic heart disease. Methods: From June 1990 to June 2001, 941 patients underwent valve replacement. Among them, 24 patients underwent simultaneously mitral, aortic and tricuspid valve replacement. There were 17 females and 7 males, with mean age of 36 years (ranged from 18 to 59 years). Eight patients had previous closed mitral valvotomy. Eleven patients complicated with left atrium thrombus, 16 with hapotomeglia, and 8 with ascites. The X ray results showed that the C/T ratio was 0.66 to 0.91. The heart function (NYHA) was class III in 9, and class IV in 15. All patients had combined mitral, aortic valve lesions associated with severe tricuspid valve regurgitation. Results: One patient died postoperatively with an operative mortality of 4.2%. 23 patients followed up from 20 to 36 months (mean, 26.4 months). There was no thrombolism and anticoagulant related hemorrhage. The echocardiography demonstrated the diameter of left atrium right ventricle, and LVDd significantly decreased after operation. The heart function was also significantly improved. Conclusion: The combination of mitral, aortic and tricuspid valve replacement could achieve a satisfactory result with low mortality and better recovery of heart function.
出处 《中华胸心血管外科杂志》 CSCD 北大核心 2003年第4期208-210,共3页 Chinese Journal of Thoracic and Cardiovascular Surgery
关键词 治疗 风湿性瓣膜病 风湿性心脏病 人工心脏瓣膜 心脏瓣膜假体植入 Rheumatic heart disease Heart valve prosthesis Heart valve prosthesis implantation
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