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慢性前列腺炎及致不育者血清及精浆抗精子抗体的研究 被引量:6

ANTISPERM ANTIBODIES IN SERUM AND SEMINAL PLASMA OF FERTILE AND INFERTILE MALES WITH CHRONIC PROSTITIS
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摘要 作者用ELISA法研究了37例慢性前列腺炎(CP)患者(其中合并不育者23例,有生育力者14例)的血清及精浆抗精子抗体(AsAb)阳性率及其与精液常规质量的联系,发现CP者与正常人间的血清AsAb阳性率无明显差别(P>0.05),说明血清AsAb与CP及其不育无明显关系。CP者的精浆AsAb阳性率(56.76%)离于正常人(18.18%)(P<0.05),且CP不育者(69.56%)又高于CP生育者(35.71%)(P<0.05),说明CP可引起精浆AsAb升高,进而降低生育力。进一步分析发现精浆AsAb阳性者的精子活动力明显降低(P<0.01),提示精浆AsAb可通过降低精子活动力进而引起不育。 Using an emzyme-Linked Immunosorbent assay (ELISA), We studied antisperm antibodies (AsAb) in serum and seminal plasma of patients suffering fram Chronic Prostatitis (CP), 23 of them are sterile, and 14 of them are fertile. We found that the incidence of AsAb in Serum have no significant difference among three groups(P>0.05), Which indicates that there is no relationship between AsAb in Serum and CP and infertility. The incidencce of AsAb in seminal plasma in cases with CP (56.76%) is significantly higher than that of normal fertile males (18.18%) (P<0.05), and that of infertile males with CP(69.56%) is again higher than that of fertile males with CP (35.71%) (P<0.05). It shows that CP can increase AsAb in Seminal plasma, which is related to sterility. Furthmore, We noted that among the infertile males with CP, sperm motility decreased in the cases with positive AsAb in seminal plasma (P<0.01), Which suggest that the decreased spern motility is related the AsAb in seminal plasma.
出处 《男性学杂志》 CSCD 1992年第4期208-211,共4页
关键词 前列腺炎 抗精子抗体 男性 不育症 Prostatitis, Infertility, Antisperm antibody.
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  • 1V. M. Bogolyubov,I. V. Karpukhin,A. S. Bobkova,A. V. Razuvayev,E. V. Kozhinova. Dynamics of spermatogenesis, hormonal and immune response of patients suffering from chronic prostatitis and sterility under bitemporal treatment with an ultra-high frequency electric field[J] 1986,International Urology and Nephrology(1):89~97

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