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重症SARS的临床治疗及疗效分析

Clinical Analysis and Therapy of Severe Acute Respiratory Syndrome
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摘要 目的探讨SARS的临床特征及治疗方法。方法对54例重症SARS患者进行回顾性分析。结果54例患者均有高热、进行性呼吸困难和肺部阴影。大多数患者ALT、AST及LDH升高。肺部和免疫系统是病毒主要作用的靶器官。治疗以综合支持对症为主,及时应用无创正压通气和大剂量糖皮质激素治疗有较好疗效。结论综合支持治疗对降低重症SARS的病死率有重要意义。 Objective To investigate the clinical features and management of critical severe acute respiratory syndrome (SARS ). Methods 54 patients with critical SARS were studied retrospectively. Results All patients manifest high fever and followed by progressive dyspnoea and appearance of lung field shadows in X rays findings. Serum ALT, AST and LDH levels were elevated in most patients. Lungs and immune system were main target organs attacked by the virus. General combination therapy was taken for treating the patients. Continual positive airway pressure (CPAP) and glucocorticoid treatments were effective for control of the disease. Conclusion Comprehensive supportive management is of paramount importance in lowering the mortality of patients with critical SARS.
出处 《热带医学杂志》 CAS 2003年第3期275-278,共4页 Journal of Tropical Medicine
基金 广州市重大科技攻关项目基金(No.2003Z1-E0011)资助。
关键词 严重急性呼吸道综合征 治疗 回顾性研究 severe acute respiratory syndrome(SARS) therapy retrospective studies
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