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梗阻性黄疸患者术后应用肠内营养对红细胞免疫功能的影响 被引量:1

Effects of postoperative enteral nutrition on immune function of red blood cell in patients with obstructive jaundice
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摘要 目的 研究术后肠内营养支持对梗阻性黄疸患者红细胞免疫功能的影响。方法 采用免疫增强型肠内营养剂对 11例梗阻性黄疸患者进行肠内喂养 ,分别于术前 1d、术后第 1、5、10天测定红细胞C3b受体花结率 (RRCR)、红细胞免疫复合物花结率 (RRICR) ,并与术后采用部分肠外营养的 10例梗阻性黄疸患者对比。结果 梗阻性黄疸患者存在着红细胞免疫功能抑制 ,术后喂养免疫增强型肠内营养剂能较快改善梗阻性黄疸患者红细胞免疫功能 ,且至术后第 10天RRCR、RRICR分别为 2 8.14± 7.0 5、5 .2 3± 1.63与对照组 2 1.2 0± 8.0 4、7.3 5± 2 .2 0相比差异均有显著性(P <0 .0 5 )。 Objective To study the effects of postoperative enteral nutrition support on red cell immune function of patients withobstructive jaundice.Methods Twenty-one patients with obstructive jaundice were divided into two groups at random,namely experimental group or enteral nutrition group (EN-group,11 cases) and obstructive jaundice control group or partial parenteral nutrition group (PPN-group,10 cases).In EN group 48 h after the operation IMPACT was pumped.In PPN-group patients were given total parenteral nutrition.Oral feeding was permitted in succession.RRCR and RRICR were measured on the day before operation and 1st,5th,10th postoperative day.Results The red cell immune function of patients with obstructive jaundice was inhibited.Pumping enteral nutrition IMPACT after operation could relieve this depression rapidly.On the 10th postoperative day there was significant difference in RRCR and RRICR in comparison with those in PPN-group (28.14±7.05 vs 21.20±8.04,5.23±1.63 vs 7.35±2.20,P<0.05).Conclusion Pumping enteral nutrition IMPACT is helpful to ameliorate red cell immune function in postoperative obstructive jaundice patients.
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2003年第9期845-846,共2页 Chinese Journal of Experimental Surgery
关键词 梗阻性黄疸 术后 肠内营养 红细胞免疫功能 RRCR RRICR Obstructive jaundice Enteral nutrition Red cell Immune
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参考文献4

  • 1郭峰 虞紫茜.红细胞免疫功能的初步研究[J].中华医学杂志,1982,62:715-717.
  • 2杨晓发,李开宗,付由池,窦科峰,郑善銮,宇传华.梗阻性黄疸患者围手术期红细胞免疫功能的临床研究[J].中华外科杂志,1995,33(7):414-417. 被引量:10
  • 3Charles J. Receptor specific clearance by the reticuloendothelia system in chronic liver diseases demonstration of defective, C3b-specific clearance in primary biliary cirrhosis.J Clin Invest, 1978, 62:1069-1075.
  • 4Bower RH, Cerra FB, Bershadsky B. Early enteral administration of a formula (Impact) supplemented with arginine, nucleotides, and fish oil in intensive care unit patients: results of a multicenter, prospective, randomized, clinical trial. Crit Care Med, 1995, 23 : 436-449.

二级参考文献4

  • 1贾士勇,国外医学外科学分册,1994年,21卷,76页
  • 2裘正军,中华实验外科杂志,1994年,11卷,9页
  • 3刘景田,红细胞免疫学新探,1993年
  • 4郭峰,中国免疫学杂志,1990年,1卷,60页

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  • 1Henderson AL,Lindorfer MA.Concerted clearance of immue complexes bound to the human erythrocyte complement recetor:development of a heterologous mouse model.J Immuo Methods,2002,270:183-197.
  • 2亓玉忠,胡三元,孙昭辉,于文滨,禹化龙.腹腔镜手术对腹腔内环境的影响[J].中华普通外科杂志,2003,18(4):234-235. 被引量:11

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