摘要
目的 探讨支原体感染的继发不孕症患者抗生素治疗前后自身抗体的变化。方法 对支原体感染的继发不孕症 16 7例进行抗精子抗体、抗子宫内膜抗体和抗心磷脂抗体的检测 ,并对自身抗体阳性的不孕症进行抗生素治疗后的复测比较。结果 支原体感染的不孕症患者中有 4 3 11% (72 /16 7)同时产生自身抗体 ,其中抗精子抗体、抗子宫内膜抗体、抗心磷脂抗体以及两项和三项复合抗体的阳性率分别为 12 5 7%、17 96 %、2 7 5 4 %、14 97% ,抗感染治疗后自身抗体均有明显减少(P <0 0 5 )。结论 支原体感染及其所诱导的自身抗体的产生是引起不孕的重要原因 ,临床诊治时应引起重视。
Objective: the purpose of this study is to examine auto-antibody changes before and after the treatment of secondary sterility patients who were affected by the Ureaplasma urealyticum (Uu) and M.hominis (Mh). Methods: 167 individuals were detected antisperm antibody(AsAb), anti-emdometrium antibody(EmAb) and antiphospholipid antibody (ACA), and the patients with auto-antibody were examined repeatedly after antibiotic treatment. Results: 43 11%(72/167) were detected auto-antibody, of the 72 cases were 12 57% AsAb,17 96% EmAb,27 54% ACA and 14 97% complex auto-antibody before antibiotic treatment. All of these auto-antibodies reduced obviously after clinical treatment.(P<0 05) Conclusion mycoplasma infection and the auto-antibody induced from mycoplasma may lead to sterilities. It is important to detect them in clinical diagnose and treatment.
出处
《中国优生与遗传杂志》
2003年第4期115-116,共2页
Chinese Journal of Birth Health & Heredity
基金
云南省卫生厅资助的科研项目 (项目号为 :2 0 0 0YWJM 10 )
