摘要
以大鼠力竭性运动为模型,观察了牛磺酸对大鼠力竭运动时心肌线粒体脂质过氧化、超氧化物歧化酶、总Ca++浓度的影响。结果显示,牛磺酸可降低大鼠力竭运动后心肌线粒体脂质过氧化水平,提高大鼠力竭运动后心肌线粒体超氧化物歧化酶(SOD)的活性,保持大鼠力竭运动后心肌线粒体总Ca++浓度。结果提示,牛磺酸可减少力竭运动后因脂质过氧化而产生的自由基,降低自由基对心肌线粒体的攻击,维持线粒体膜的功能,说明牛磺酸有保护心肌线粒体的功能和防止心肌线粒体损伤的作用。
Taking the incremental exercise to exhaustion as an example,the author observes the MDA content,SOD activity and total calcium concentration of the myocardial mitochondria in rats at rest and immediately after exhaustion supplied with 1% taurine in drinking water.The result shows that taurine supplement can decrease the lipid peroxidation level,SOD activities and total calcium concentration significantly in the myocardial mitochondria of rats after exhaustive exercise.These finding suggests that taurine can decrease free radicals,protect the damage of myocardial mitochondria against the lipid peroxidation,retain the function of myocardial mitochondria.
出处
《中国体育科技》
北大核心
2003年第2期27-28,48,共3页
China Sport Science and Technology
基金
广东省自然科学基金重点项目(粤高教科[1999]89)。
关键词
牛磺酸
心肌
线粒体
自由基
鼠
力竭运动
动物实验
taurine
myocardial
mitochondrion
free radicals
rat
exhaustive exercise
animac experiment
