摘要
目的 :探讨米索前列醇联合催产素在产后应用的作用及其意义。方法 :将患者分为三组 ,研究组使用米索前列醇联合催产素 ;对照组 1使用催产素 ;对照组 2使用米索前列醇 ,分别观察产后大出血发生率及第一时段 (胎儿娩出后至胎盘娩出 )和第二时段 (胎盘娩出后至产后 2h)的平均出血量。结果 :产后大出血发生率 :研究组产后出血率为 2 .5 % ,低于对照组 1的 9.2 % (x2 =4 .85p <0 .0 5有可比性 ) ,也低于对照组 2的 8.3% (x2 =3.99p <0 .0 5有可比性 )。第一时段平均出血量 :研究组为15 7.1± 6 0 .3(ml) ,对照组 1为 180 .1± 70 .4 (ml) ,对照组 2为 173.9± 5 2 .3(ml)。研究组与对照组 1比较t=2 .71p <0 .0 1有可比性 ,与对照组 2比较t=2 .30p <0 .0 5有可比性。第二时段平均出血量 :研究组为 6 8.3± 38.7(ml) ,对照组 1为 84 .2± 4 7.2 (ml) ,对照组 2为 79.7± 4 2 .6 (ml)。研究组与对照组 1比较t=2 .85p <0 .0 1有可比性。研究组与对照组 2比较t=2 .17p <0 .0 5有可比性。结论 :米索前列醇联合催产素可减少产后出血量 ,对预防产后大出血的发生有一定意义。
Objective: To investigate the significance and the effect of combining use Misoprostol and Oxytocin in post parturition. Method: Divided the patients into 3 groups. The study group was for combining use of Misoprostol and Oxytocin; The control group 1 was for Oxytocin;The control group 2 was for Misoprostol. Observed the rate of postpartum massive hemorrhage,average amount of the blood in the first period (the period from childbearing to the delivery of placenta ) and the second period(the period from the delivery of placenta to 2 hours post parturition ). Result: The rate for postpartum hemorrhage: study group was 2.5%, lower than that of control group 1 of 9.2% (x 2=4.85,P<0.05), also lower than that of control group 2 of 8.3% (x 2=3.99,P<0.05). The differences were statistically significant. The amount for the first period: study group was 157.1±60.3(ml), the control group 1 was 180.1±70.4(ml), the control group 2 was 173.9±52.3(ml)。The differences that the study group compared with the control group 1(t=2.71 P<0.01) and compared with the control group 2(t=2.30 p<0.05) were statistically significant. The amount for the second period: study group was 68.3±38.7(ml),the control group 1 was 84.2±47.2ml), the control group 2 was 79.7±42.6(ml)。The differences that the study group compared with the control group 1(t=2.85 p<0.01) and compared with the control group 2 (t=2.17 p<0.05) were statistically significant. Conclusion:The combining use of Misoprostol and Oxytocin is effective in the prevention of postpartum hemorrhage and reduction of the amount of postpartum hemorrhage.
出处
《河北医学》
CAS
2003年第7期599-601,共3页
Hebei Medicine
