摘要
生物吸收性合成聚酯纤维常用作外科手术缝合线。这种合成可吸收缝合线(SAS)优于非生物降解的天然和合成材料,它们在体内是通过水解降解成为无毒产物并最终为组织吸收。在降解过程中,材料的结晶度对合成可吸收缝合线水解降解过程的影响是很重要的。本文通过对微原纤晶体结构模型和Swiss—Cheese晶体模型的描述,对几种SAS在降解过程中结晶度、降解性能和力学性能的变化进行了阐述。
In the hydrolytic degradation, the degree of crystallinity of absorbable suture is one of the basic physical properties. The importance of this property has been shown during hydrolytic degradation since hydrolytic degradation would destroy the crystalline structure and properties of suture. Two kind models of fiber structure are given in this article: one is the microfibrillar model which combines the concepts of the folded chain, the other is Swiss-Cheese structural model which consists of three domains differing in density and molecular orientation. The concept of microfibrillar structure of fibres and Swiss-Cheese structural model provides the basis for the proposed degradation mechanism of PGA, PDS and PDG hydrolytic degradation in vitro.
出处
《天津轻工业学院学报》
2003年第3期30-34,共5页
Journal of Tianjin University of Light Industry
