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大剂量化疗不加全身放疗行自体骨髓移植治疗急性髓细胞性白血病 被引量:1

Autologous Bone Marrow Transplantation with High Dose Chemotherapy Without "TBI" in Acute Myeloid Leukemia
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摘要 本文报告9例急性髓细胞性白血病在首次缓解期单用大剂量化疗不加全身放疗(TBI)行未净化自体骨髓移植(ABMT)治疗,经远期随访观察,结果有4例(44.4%)移植后分别已无病存活36、39、44和58个月,另5例(55.6%)则在移植后3.5~12.5个月时死于白血病复发。 Nine patients with acute myeloid leukemia were treated by unpured autolo-gous bone marrow transplantation (ABMT) in first complete remission. The conditioning regimen mainly consisted of BCNU, AMSA. VP_(16) and Ara-C withouttotal body irradiation. Nausea and vomiting were common. The median time from first com-plete remission to ABMT was 142 days. The results of follow-up were as follows: 4 patientsare well and alive with disease-free state at 36, 39, 44 and 58 months respectively afterABMT. Other 5 patients relapsed precociously and died during 3.5~12.5 months afterABMT.
出处 《临床血液学杂志》 CAS 1992年第3期105-107,104,共4页 Journal of Clinical Hematology
关键词 自体 骨髓移植 白血病 药物疗法 Acute myeloid leukemia Autologous bone marrow transplantation.
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