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自身骨髓移植在晚期恶性肿瘤治疗中的应用

Clinical Studics of Autologous Bone Marrow Transplantation in the Treatment of the Patients with Advanced Malignancies
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摘要 本文报导我院1980~1991年6月因患各种晚期恶性肿瘤,主要是儿童恶性肿瘤患者50例,接受强化疗及自身骨髓移植治疗的临床小结。结果示(1)自身骨髓移植对治疗小儿恶性脑瘤、淋巴瘤、神经母细胞瘤等均有一定疗效,脑瘤组最明显;(2)脑瘤组在移植后需继续维持化疗3年左右,以防复发;(3)无论晚期淋巴瘤、神经母细胞瘤、急性白血病,在完全缓解期作移植,疗效好。(4)50例作自身移植者的结果提示自身骨髓移植对治疗晚期恶性肿瘤,是一种较安全、有效、值得采用的方法。 The clinical experience on 50 patients with various advanced malignancies,most of them are children, treated with aggressive chemotherapy and autologous bone mar-row transplantation (ABMT) from 1980 to June 1991, was surmerized in this report. Thedata showed that(1)it's effective for the ABMT in the treatment of children with advancedm(?)lignancies, such as brain tumors, Non-Hodgkin's lymphoma and neuroblastoma, partic-ularly in brain tumors. (2) the maintainance chemotherapy should still be needed afterABMT for over 3 years to prevent relapse. (3) no matter which form of advanced malig-nancies, the key is to do ABMT in remission Period, otherwise the results were poor. (4)theresults of ABMT 50 cases indicated that ABMT is safe and quite helpful for the treatment ofvarious advanced malignancies and worth of wide applicatiom.
出处 《临床血液学杂志》 CAS 1992年第3期101-104,共4页 Journal of Clinical Hematology
关键词 恶性 肿瘤 自身 骨髓移植 Malignancies Autologous bone marrow transplantation.
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