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自杀基因在异基因骨髓移植中的应用 被引量：1

The study of suicide gene in allogenetic bone marrow transplantation
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摘要 异基因骨髓移植 (allo BMT)是治愈恶性血液系统疾病的重要方法之一 ,但其并发症移植物抗宿主病 (GVHD)限制了其在临床上的发展应用。国内外不少研究表明自杀基因转染T淋巴细胞可控制移植物抗宿主病。
作者 姜义荣 马道新 陈学良 刘春生
机构地区 山东大学齐鲁医院血液内科
出处 《国外医学（肿瘤学分册）》 2003年第4期311-314,共4页 Foreign Medical Sciences (Cancer Section)
基金 国家自然科学基金资助项目 (30 0 70 32 1)
关键词 异基因骨髓移植 自杀基因 T淋巴细胞 移植物抗宿主病
分类号 R457.7 [医药卫生—治疗学]
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参考文献24

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同被引文献21

  • 1Ichiki Y,Bowlus CL,Shimoda S,et al.T cell immunity and graftversus-host disease(GVHD).Autoimmun Rev,2006;5(1):1～9.
  • 2Min CK,Maeda Y,Lowler K,et al.Paradoxical effects of interleukin-18 on the severity of acute graft-versus-host disease mediated by CD4+ and CD8+ T-cell subsets after experimental allogeneic bone marrow transplantation,Blood,2004;104(10):3393-3399.
  • 3Franzke A,Piao W,Lauber J.G-CSF as immune regulator in T cells expressing the G-CSF receptor:implications for transplantation and autoimmune diseases.Blood,2003;102(2):734-739.
  • 4Devine SM,Brown RA,Mathews V,et al.Reduced risk of acute GVHD following mobilization of HIA-identical sibling donors with GM-CSF alone.Bone Marrow Transplant,2005;36(6):531-538.
  • 5Kuroiwa T,Kakishita E,Hamano T,et al.Hepatoeyte growth factor ameliorates acute graft-versus-host disease and promotes hematopeietic function.J Clin Invest,2001;107(11):1365-1373.
  • 6Imado T,Iwasaki T,Kataoka Y.Hepatocyte growth factor preserves graft-versus-leukemia effect and T-cell reconstitution after marrow transplantation.Blood,2004;104(5):1542-1549.
  • 7Duffner U,Lu B,Hildebrandt GC.Role of CXCR3-induced donor T-cell migration in acute GVHD.Exp Hematol,2003;31(10):897-902.
  • 8Varona R,Cadenas V,Gomez L,et al.CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses.Blood,2005;106(1):18-26.
  • 9Jones SC,Mushy GF,Korngold R.Post-hematopeietic cell transplantation control of graft-versus-host disease by donor CD4+25+T cells to allow an effective graft-remus-leukemia response.Biol Blood Marrow Transplant,2003;9(4):243-256.
  • 10Kataoka Y,Iwasaki T,Kuroiwra T,et al,The role of donor T cells for target organ injuries in acute and chronic graft-versus host discase.Immunology,2001;103(3):310-318.

引证文献1

国外医学（肿瘤学分册）
2003年 第4期

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